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Elsberg syndrome - A systematic review of existing scientific literature from 2000 - 2023.
Pak J Med Sci
December 2024
Dr. Asif Bashir, MD; FAANC; FACS, Punjab Institute of Neurosciences, Lahore, Punjab, Pakistan.
Objective: To assess the clinical presentation, causative agents, and treatment outcomes in patients diagnosed with Elsberg syndrome (ES).
Methods: A thorough literature search was conducted on the mentioned topic using PRISMA guidelines via PubMed, Google Scholar, and SCOPUS. Articles published between 2000 and 2023 were included using advanced search and Boolean strategy.
The Role of Varicella Zoster Virus (VZV) in Central Nervous System Infectious Syndromes.
Can J Infect Dis Med Microbiol
November 2024
Infection Diseases Department, Kaplan Medical Center, Rehovot, Israel.
We describe the proportion of VZV infection in central nervous system (CNS) infectious syndromes in a single Israeli medical center. An observational cohort study was conducted in Kaplan Medical Center (a secondary hospital, Israel) between July 1, 2014, and March 31, 2019. Included were adult patients (≥ 16 years old) with CNS infection with an aseptic CSF profile that were subjected to molecular tests for herpes viruses, HSV either 1 or 2, VZV, enteroviruses, and IgM for West Nile virus (WNV).
View Article and Find Full Text PDFTargeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens.
J Transl Med
July 2024
Research Group Biomarkers for Infectious Diseases, TWINCORE Centre for Experimental and Clinical Infection Research, Feodor-Lynen-Str. 7, 30625, Hannover, Germany.
Article Synopsis
- * A study analyzed CSF from COVID-19 patients with neurological issues, comparing it to cases of viral CNS infections and aseptic neuroinflammation, focusing on differences in metabolic profiles.
- * Results showed low neuroinflammation in neuro-COVID, with specific metabolites like citrulline and ceramide significantly increased, while triglyceride levels were notably lower, indicating distinct metabolic pathways compared to other CNS infections.
Varicella-zoster virus-related neurological complications: From infection to immunomodulatory therapies.
Rev Med Virol
July 2024
Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
The Varicella-zoster virus (VZV), classified as a neurotropic member of the Herpesviridae family, exhibits a characteristic pathogenicity, predominantly inducing varicella, commonly known as chickenpox, during the initial infectious phase, and triggering the reactivation of herpes zoster, more commonly recognized as shingles, following its emergence from a latent state. The pathogenesis of VZV-associated neuroinflammation involves a complex interplay between viral replication within sensory ganglia and immune-mediated responses that contribute to tissue damage and dysfunction. Upon primary infection, VZV gains access to sensory ganglia, establishing latent infection within neurons.
View Article and Find Full Text PDFThe history of the Japanese Society for Neuro-infectious Diseases: Foundation, objectives, and legacy.
Intractable Rare Dis Res
May 2024
Department of Cerebral-Neurology, St. Marianna Medical College, Yokohama, Japan.
The Japanese Research Group for Neuro-infectious Diseases was founded in August 1996, and by 2004 it had evolved into the Japanese Society for Neuro-infectious Diseases. The Society focuses on neuroinfectious conditions (., encephalitis/encephalopathy, myelitis, and meningitis), providing a venue for academic presentations and exchanges.
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