The article deals with the therapy of cancer of the cervix with external 42 MeV betatron bremsstrahlung irradiation in combination with intracavitary applicated radium. The described irradiation technique using special shielding blocks extends the dose distribution till to the region of paraaortic nodes in an extended field. The extended irradiation field is used on the basis of lymphographic examination. In the region of pelvis minor, sufficiently uniform dose distribution is attained with lethal tumor effect. The dose variability with betatron or cobalt external irradiation was also studied.
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Phys Rev Lett
December 2024
Stanford University, Department of Mechanical Engineering, Stanford, California 94305, USA.
The extreme electric fields created in high-intensity laser-plasma interactions could generate energetic ions far more compactly than traditional accelerators. Despite this promise, laser-plasma accelerator experiments have been limited to maximum ion energies of ∼100 MeV/nucleon. The central challenge is the low charge-to-mass ratio of ions, which has precluded one of the most successful approaches used for electrons: laser wakefield acceleration.
View Article and Find Full Text PDFAppl Radiat Isot
March 2025
Kyoto University Graduate School of Engineering, Kyoto Daigaku-katsura, Nishikyo-ku, Kyoto, 615-8530, Japan.
We aimed to explore the possibility of realizing a beam shaping assembly (BSA) driven by a 15-kW beam of 33-MeV electrons of an electron linear accelerator (LINAC) when a boronophenylalanine is adopted as a boron carrier. Simulation calculations were performed to design two types of BSAs driven by the small LINAC. The one was an experimental BSA, and the other was a high-performance BSA.
View Article and Find Full Text PDFSci Rep
December 2024
SANKEN (Institute of Scientific and Industrial Research), Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka, 567-0047, Japan.
By employing the stabilizer in the supersonic gas nozzle to produce the plasma density profile with a sharp downramp, we have experimentally demonstrated highly stable electron beam acceleration based on the shock injection mechanism in laser wakefield acceleration with the use of a compact Ti:sapphire laser. A quasi-monoenergetic electron beam with a peak energy of 315 MeV ± 12.5 MeV per shot is generated.
View Article and Find Full Text PDFPhys Med
January 2025
Dosimetry for Radiation Therapy and Diagnostic Radiology, Physikalisch-Technische Bundesanstalt (PTB), Braunschweig 38116, Germany; Metrology Research Center, National Research Council of Canada, 1200 Montreal Road, Ottawa, ON, K1A0R6, Canada.
Background: FLASH radiotherapy necessitates the development of advanced Quality Assurance methods and detectors for accurate monitoring of the radiation field. This study introduces enhanced time-resolution detection systems and methods used to measure the delivered number of pulses, investigate temporal structure of individual pulses and dose-per-pulse (DPP) based on secondary radiation particles produced in the experimental room.
Methods: A 20 MeV electron beam generated from a linear accelerator (LINAC) was delivered to a water phantom.
PLoS One
December 2024
Northwest Institute of Nuclear Technology, Xian Shi, Shannxi, China.
Beam energy, normalized emittance, and quantum efficiency are crucial parameters of the RF gun. In this study, we proposed a compact and low-cost method to measure the beam energy at the exit of the 120 MeV electron linac's RF gun. We utilized a solenoid magnetic field to rotate an elliptical beam and measured the rotation angle of the beam to calculate the energy.
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