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[Pain around the first ray of the hand: differential diagnoses and treatment].

Orthopadie (Heidelb)

January 2025

Klinik für Handchirurgie und Orthopädie, Spital Langenthal, Spital Region Oberaargau SRO AG, Langenthal, Schweiz.

Pain around the first ray of the hand, particularly in the thumb area, is a frequent clinical problem that can have various causes. This article explores the most important differential diagnoses, including thumb carpometacarpal (CMC-I) osteoarthritis (rhizarthrosis), de Quervain's stenosing tenosynovitis, carpal tunnel syndrome and Wartenberg's syndrome. A detailed medical history, targeted clinical examination and if necessary the use of modern imaging techniques are crucial for making the diagnosis.

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Objective: The aim of this study was to establish a three-dimensional finite element (FE) hydraulic pressure technique model and compare the biomechanical characteristics of the osteotome technique and the hydraulic pressure technique using three-dimensional finite element analysis (FEA).

Methods: Three FE models were created: the hydraulic pressure technique (M1), the osteotome technique with a Ø 1.6-mm osteotome (M2), and the osteotome technique with a Ø 3.

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[Pathology of the spleen : Differential diagnosis of splenomegaly].

Pathologie (Heidelb)

January 2025

Institut für Pathologie, Universitätsmedizin Göttingen, Universität Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland.

After describing the anatomy of the spleen and the most important immunohistochemical stains for identifying cellular constituents of the normal splenic compartments, etiologies of splenomegaly and the diagnostic approach for spleen biopsies are discussed using the example of a North African patient with a recent migration background and sudden fever. The focus is on infectious diseases and the morphology and molecular features of hematolymphoid neoplasms, particularly the primary "splenic B‑cell lymphomas" according to the World Health Organization (WHO) classification. The importance of clinicopathological correlations and interdisciplinary cooperation in splenic pathology is emphasized.

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Case report: Endolymphatic sac tumor with blurred vision.

Front Oncol

January 2025

The Second Clinical Medicine College, Jinan University, Shenzhen, China.

Introduction: Endolymphatic sac tumor (ELST) is a rare neoplasm that exhibits aggressive growth primarily in the endolymphatic capsule and can potentially affect nearby neurovascular structures. The diagnosis of ELST poses challenges due to its low prevalence, gradual progression, and nonspecific symptomatology. It is currently believed that prompt surgical intervention is recommended for endolymphatic sac tumors upon diagnosis.

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[Diagnosis of pediatric melanocytic tumors].

Dermatologie (Heidelb)

January 2025

Universitäts-Hautklinik Tübingen, Liebermeisterstr. 25, 72076, Tübingen, Deutschland.

The histological diagnosis of pediatric melanocytic tumors is challenging, as benign nevi often resemble aggressive tumors. Accurate diagnosis is crucial for the early detection of rare pediatric melanomas. Recent advancements have established a classification based on genetic backgrounds.

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