In anesthesized cats inspiratory activity of the respiratory center at first increased and then decreased with increases in total pressure of the nitrogen-oxygen atmosphere to 7, 11, and 21 atm (at normal PO2). The effort made by respiratory muscles increased gradually. These changes were augmented by hypercapnia. Possible role of nitrogen anesthesia and compensatory reactions to the increased breathing resistance in the department of the above changes is discussed.

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