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Predicting phage-host interaction via hyperbolic Poincaré graph embedding and large-scale protein language technique.
iScience
January 2025
Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi'an 710069, China.
Bacteriophages (phages) are increasingly viewed as a promising alternative for the treatment of antibiotic-resistant bacterial infections. However, the diversity of host ranges complicates the identification of target phages. Existing computational tools often fail to accurately identify phages across different bacterial species.
View Article and Find Full Text PDFEffect of pH and temperature on the stability of the natural dye from the roselle flower ( L.) and its application in flavored milk.
J Food Sci Technol
January 2025
Department of Food Engineering, University of Córdoba, 230007 Montería, Colombia.
In recent years, global trends indicate consumer interest in functional foods. Thus, there is a trend to replace the use of artificial colors with natural colors that, in addition to being attractive to consumers, provide benefits to the biological functions of the human organism. The objective of this research was the solvent extraction of a natural dye from the roselle flower, its identification and evaluation of its behavior at different pH and temperatures.
View Article and Find Full Text PDFBiomaterial-assisted organoid technology for disease modeling and drug screening.
Mater Today Bio
February 2025
The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Developing disease models and screening for effective drugs are key areas of modern medical research. Traditional methodologies frequently fall short in precisely replicating the intricate architecture of bodily tissues and organs. Nevertheless, recent advancements in biomaterial-assisted organoid technology have ushered in a paradigm shift in biomedical research.
View Article and Find Full Text PDFArtificial intelligence-powered innovations in periodontal diagnosis: a new era in dental healthcare.
Front Med Technol
January 2025
Ph.D. in Health Science Program, Faculty of Medicine, Mahasarakham University, Mahasarakham, Thailand.
Background: The aging population is increasingly affected by periodontal disease, a condition often overlooked due to its asymptomatic nature. Despite its silent onset, periodontitis is linked to various systemic conditions, contributing to severe complications and a reduced quality of life. With over a billion people globally affected, periodontal diseases present a significant public health challenge.
View Article and Find Full Text PDF"Having providers who are trained and have empathy is life-saving": Improving primary care communication through thematic analysis with ChatGPT and human expertise.
PEC Innov
June 2025
University of Rhode Island, 142 Flagg Road, Chafee Hall, Department of Psychology, Kingston, RI 02881, USA.
In the rapidly evolving field of healthcare research, Artificial Intelligence (AI) and conversational models like ChatGPT (Conversational Generative Pre-trained Transformer) offer promising tools for data analysis. The aim of this study was to: 1) apply ChatGPT methodology alongside human coding to analyze qualitative health services feedback, and 2) examine healthcare experiences among lesbian, gay, bisexual, transgender, and queer (LGBTQ+) patients ( = 41) to inform future intervention. The hybrid approach facilitated the identification of themes related to affirming care practices, provider education, communicative challenges and successes, and environmental cues.
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