It was found in vitro that desoxycholic, cholic, glycocholic and choleinic acids inhibited the growth and development of staphylococci. The staphylococci isolated from bile were more resistant to the bacteriostatic and bactericidal effect of bile acids than the microorganisms isolated from other sources not containing cholates. Under the effect of these substances the activity of some antibiotics especially those from the group of aminoglycosides markedly increased.
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