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Associations between prenatal exposure to metal mixtures and infant reproductive hormones during mini-puberty.
Sci Total Environ
December 2024
Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tong ji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address:
Background: The reproductive hormone homeostasis is crucial for child development. Exposure to metals during pregnancy may have adverse effects on offspring health. However, the association between prenatal exposure to metals and infant reproductive hormone levels remains unknown.
View Article and Find Full Text PDFReproductive Hormones Imbalance, Germ Cell Apoptosis, Abnormal Sperm Morphophenotypes and Ultrastructural Changes in Testis of African Giant Rats (Cricetomys gambianus) Exposed to Sodium Metavanadate Intoxication.
Environ Sci Pollut Res Int
June 2022
Department of Veterinary Anatomy, University of Ibadan, Ibadan, Nigeria.
Environmental exposure to vanadium has been on the increase in recent time. This metal is a known toxicant. The current study was conducted to investigate the reproductive toxicity of sodium metavanadate (SMV) in male African giant rats.
View Article and Find Full Text PDFProtection against vanadium-induced testicular toxicity by testosterone propionate in rats.
Toxicol Mech Methods
July 2010
Endocrinology & Reproductive Physiology Laboratory, Department of Physiology, University of Calcutta, 92 Acharya Prafulla Chandra Road, Kolkata, West Bengal, India.
Vanadium is a well recognized industrial hazard known to adversely affect male reproductive functions. The intricate mechanistic aspects of this metal and the role of oxidative stress in the deterioration of testicular functions are investigated in the current study. The experiment also focused on the effects of testosterone propionate in testicular and sperm functions in the rat intoxicated with vanadate.
View Article and Find Full Text PDFWe have appraised the properties of steady state calcium exchange in cultured swine granulosa cells prelabeled to isotopic equilibrium with 45Ca2+. Subsequent steady state efflux parameters were assessed by nonlinear least-squares curve-fitting to a two-compartment model. The resultant mean rate constants were 0.
View Article and Find Full Text PDFThe effect of forskolin on the hormonal (LH, FSH) activation and on the stimulation provided by other effectors (Gpp(NH)p,NaF) of the juvenile rat ovarian adenylate cyclase was investigated. Forskolin exhibited a synergistic action with LH, FSH and Gpp(NH)p but not with NaF. Addition of Ca2+ was inhibitory over a concentration range from 10(-5) to 10(-2) M whereas EGTA enhanced the response at 5.
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