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Estradiol Levels are Differentially Associated with Pulse Wave Velocity in Trauma-exposed Premenopausal Women with and without PTSD.
Am J Physiol Regul Integr Comp Physiol
January 2025
Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, MN.
Arterial stiffness is a well-known risk factor for cardiovascular disease. Although estradiol (E2) is known to be cardioprotective, the available data point to a growing cardiovascular disease risk in women before menopause due to post-traumatic stress disorder (PTSD). The present study aimed to investigate the effects of E2 on arterial compliance in trauma-exposed premenopausal women, with and without a clinical diagnosis PTSD.
View Article and Find Full Text PDFManifestations of human atherosclerosis across vascular beds.
JVS Vasc Insights
May 2024
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University.
Objective: Atherosclerosis underlies the most common etiologies of mortality worldwide, resulting in nearly 10 million deaths annually. In atherosclerosis, inflammation, metabolic factors, and hemodynamics cause the accumulation of extracellular lipids and the formation of plaques in the tunica intima of specific arteries. Atherosclerotic plaques primarily form in the coronary and carotid arteries, the aorta, and the peripheral arteries of the lower extremities.
View Article and Find Full Text PDFComparison of Influence of Office and 24-h Central Aortic Blood Pressure on Target Organ Damage in Hypertension.
J Clin Hypertens (Greenwich)
January 2025
Department of Geriatrics, Medical Center on Aging of Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
The aim of this study was to explore whether 24-h ambulatory central (aortic) blood pressure (BP) has an advantage over office central aortic BP in screening for hypertension-mediated target organ damage (HMOD). A total of 714 inpatients with primary hypertension and the presence of several cardiovascular risk factors or complications involving clinical HMOD were enrolled. Twenty-four hour central aortic BP was measured by means of a noninvasive automated oscillometric device (Mobil-O-Graph).
View Article and Find Full Text PDFAssociation of Red Blood Cell Distribution Width With Carotid-Femoral Pulse Wave Velocity in a Southern Chinese Population.
J Clin Hypertens (Greenwich)
January 2025
Department of Geriatrics, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Red blood cell distribution width (RDW) has recently been recognized as a novel biomarker associated with various cardiovascular conditions. This study aims to investigate the relationship between RDW and carotid-femoral pulse wave velocity (cfPWV) in a southern Chinese population. A total of 4916 patients were initially enrolled from the First Affiliated Hospital of Fujian Medical University between January 2016 and December 2022.
View Article and Find Full Text PDFAssociation of maternal body mass index with hemodynamic and vascular alterations at 35-37 weeks' gestation.
Ultrasound Obstet Gynecol
January 2025
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, UK.
Objective: Globally, one in four pregnant women is classified as overweight or obese, based on their prepregnancy body mass index (BMI). Obese pregnant women are at increased risk of adverse pregnancy outcomes and long-term cardiovascular disease that occurs earlier in life. This study aimed to assess maternal hemodynamic and vascular parameters at 35-37 weeks' gestation, to understand the alterations that may occur in association with increased maternal BMI and gestational weight gain, and to evaluate obesity-related pregnancy outcomes.
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