Continuously monitored carotid arterial PO2 (PaO2) and transcutaneous PO2 (tcPO2) from the scalp of fetuses from ewes not in labor have been compared under epidural anesthesia at different levels of fetal oxygenation. A reasonably good correlation existed between the two readings at normal and high PO2 values. In sharp contrast, at low PaO2 levels there was a considerable bias between the two. Since this bias was variable, the failure of tcPO2 to reflect PaO2 accurately at low PaO2 renders the use of the tcPO2 electrode questionable in the very situation for which it was advocated, namely, the prediction of fetal compromise.
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http://dx.doi.org/10.1016/0002-9378(80)90086-1 | DOI Listing |
BMC Anesthesiol
January 2025
Department of Anesthesiology and Reanimation, University of Health Sciences, Gulhane Training and Research Hospital, Etlik, Ankara, 06010, Turkey.
Introduction-objective: Hyperoxia is associated with acute lung injury and atelectasis. Arterial blood gas measurement is an invasive method. The Oxygen Reserve Index (ORI) was developed to monitor the oxygen values of patients.
View Article and Find Full Text PDFFront Pediatr
January 2025
Department of Anesthesiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Objective: To discover the potential association between diminished intraoperative average SctO levels and postoperative neurodevelopmental delays among patients after pediatric living-donor liver transplantation.
Study Design: Patients undergoing living-donor liver transplantation were recruited for this trial. The neurodevelopment status of patients was assessed using the Ages Stages Questionnaires.
Front Vet Sci
January 2025
Department of Clinical Sciences, Ross University School of Veterinary Medicine, Basseterre, Saint Kitts and Nevis.
The oxygen reserve index (ORi) is a novel, non-invasive parameter that estimates arterial oxygen partial pressure (PaO) during hyperoxia when the fraction of inspired oxygen (FiO) is elevated. This study aimed to assess the utility of the ORi/FiO ratio as an index for quantifying F-shunt, serving as an estimate of venous admixture. Anesthetic records were reviewed from 44 dogs undergoing general anesthesia and requiring arterial catheterization.
View Article and Find Full Text PDFScand J Trauma Resusc Emerg Med
January 2025
Department of Acute Care, University Medical Centre Groningen, Groningen, the Netherlands.
Background: As iatrogenic hyperoxia has been related to adverse outcomes in critically ill patients, guidelines advise to titrate oxygen to physiological levels. In the prehospital setting where partial arterial oxygen (PaO) values are often not readily available, titration of oxygen is based on peripheral oxygen saturations (SpO2). In this study we aimed to investigate the efficacy of SpO guided oxygen titration in the prevention of hyperoxia.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Pathology, Dokkyo Medical University School of Medicine and Graduate School of Medicine, 880 Kitakobayashi, Mibu, Shimotsugagun, Tochigi, 321-0293, Japan.
Although alveolar hyperoxia exacerbates lung injury, clinical studies have failed to demonstrate the beneficial effects of lowering the fraction of inspired oxygen (FO) in patients with acute respiratory distress syndrome (ARDS). Atelectasis, which is commonly observed in ARDS, not only leads to hypoxemia but also contributes to lung injury through hypoxia-induced alveolar tissue inflammation. Therefore, it is possible that excessively low FO may enhance hypoxia-induced inflammation in atelectasis, and raising FO to an appropriate level may be a reasonable strategy for its mitigation.
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