The radiologic changes in 1090 cases of lymphoma of the small bowel were analyzed and correlated with the pathologic findings. The material was collected in Iran, a high incidence area for immunoproliferative small bowel disease (IPSID). Of 100 cases of primary intestinal lymphoma associated with IPSID, 48 involved the duodenum and upper jejunum. They were associated with a characteristic spruelike radiologic pattern of the nonlymphomatous segments of the gut, the intensity of which decreased distally. However, the radiologic features of the lymphoma associated with IPSID were identical with those described in other forms of primary small intestinal lymphoma, regardless of histologic type or the presence and absence of alpha-heavy chain secretion.
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http://dx.doi.org/10.2214/ajr.135.3.491 | DOI Listing |
Cureus
June 2024
Department of Gastroenterology and Hepatology, Rutgers New Jersey Medical School, Newark, USA.
Indian J Gastroenterol
October 2023
Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, 110 029, New Delhi, India.
Immunoproliferative small intestinal disease (IPSID) is an uncommon disease of the small intestine. There is a similarity in the clinical presentations of enteropathic diseases, including celiac disease, tropical sprue, IPSID, and Whipple's disease. A differentiation between them is based on the use of a highly specific serological test for celiac disease and specific histological characteristics.
View Article and Find Full Text PDFCurr Oncol
May 2022
Section of Hematology and Bone Marrow Transplant, King Faisal Specialist Hospital and Research Center, Riyadh 11564, Saudi Arabia.
Immunoproliferative small intestinal disease (IPSID) is an uncommon disease with a higher prevalence in the developing world. IPSID diagnosis relies mainly on a tissue biopsy and a high index of suspicion. Treatment options are variable; however, they mainly include anthracycline-based chemotherapy with or without antibiotics in advanced stages.
View Article and Find Full Text PDFIntern Med
September 2022
Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Japan.
We herein report an 80-year-old man diagnosed with immunoproliferative small intestine disease (IPSID) via small bowel endoscopy with a biopsy. He developed persistent diarrhea and subsequently presented with hypoproteinemia and moderate anemia. Transanal double-balloon endoscopy showed prominent villous edema in the middle and lower ileum, while a histological examination showed high lymphocyte/plasma cell infiltration in the mucosal layer.
View Article and Find Full Text PDFCancers (Basel)
January 2022
Department of Gastroenterology, International University of Health and Welfare, Fukuoka 814-0001, Japan.
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) typically arises from sites such as the stomach, where there is no organized lymphoid tissue. Close associations between and gastric MALT lymphoma or and immunoproliferative small intestinal disease (IPSID) have been established. A subset of tumors is associated with chromosomal rearrangement and/or genetic alterations.
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