An extraction and electrophoresis of histones from normal and starved Euglena cell nuclei allows us to show the presence of five types of histones in the two cases but a lower degree of acetylation appears in H4 histone from starved cells. It was shown that DNA repeat length from the two kinds of chromatin is comparable (225 b.p.).
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Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial.
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British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, UK. Electronic address:
Background: Data on the effect of mineralocorticoid receptor antagonist therapy on HbA levels and new-onset diabetes are conflicting. We aimed to examine the effect of oral finerenone, compared with placebo, on incident diabetes in the Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients with Heart Failure (FINEARTS-HF) trial.
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January 2025
Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 China
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