AI Article Synopsis
- A single injection of 4.5 mg/kg of diacetoxyscirpenol, a toxin from the Fusarium fungus, enhances the development of candidiasis in mice infected with C. albicans.
- After 24 hours of incubation, C. albicans colonies were counted from the homogenized kidney samples spread on Sabouraud dextrose agar plates.
- The comparison of mean values from the infected kidneys showed highly significant differences between those exposed to C. albicans alone and those exposed to both C. albicans and the toxin.
Article Abstract
A single injection of 4.5 mg/kg of diacetoxyscirpenol (a toxin synthesized by Fusarium) into Mice challenged by C. albicans, increases significantly the development of an experimental candidiasis. Suspensions of homogenized kidneys was spread on Sabouraud dextrose agar plates and the colonies of C. albicans were counted after 24 hrs incubation. The mean values were determined. Comparison of mean values calculated for kidneys from the Mice challenged with C. albicans and those challenged with C. albicans plus toxin gave highly significant results.
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