AI Article Synopsis

  • The study analyzed 52 patients who underwent spleno-pancreatogastrectomy, revealing a mortality rate of 25% and varying survival rates over 3, 5, and 10 years, with 28%, 14.7%, and 9% respectively.
  • While carbohydrate metabolism showed minor changes not needing intervention, the activity of the cholinergic system was reduced, negatively impacting respiratory function and basic metabolism.
  • The findings suggest incorporating cholinomimetics and lipocain in postoperative care to address these issues.

Article Abstract

Clinico-physiological data on 52 patients after spleno-pancreatogastrectomy are analysed. The mortality was 25%, the late results were as follows: a 3-year survival--in 28%, a 5-year survival--in 14.7%, a 10-year survival--in 9%. This group of patients was examined for the functional state of the cholinergic system, carbohydrate metabolism, external respiration and basic metabolism. Carbohydrate metabolism is found to change but insignificantly and requires no corrective measures. The cholinergic system activity was reduced, that adversely affects the respiratory function and contributes to the decreased basic metabolism. The latter would necessitate including of cholinomimetics and lipocain in the scheme of the postoperative management.

Download full-text PDF

Source

Publication Analysis

Top Keywords

cholinergic system
8
carbohydrate metabolism
8
basic metabolism
8
[clinical physiological
4
physiological evaluation
4
evaluation splenopancreatogastrectomy
4
splenopancreatogastrectomy operation
4
operation stomach
4
stomach cancer
4
cancer patients]
4

Similar Publications

The vagus nerve (VN) is the primary parasympathetic nerve, providing two-way communication between the body and brain through a network of afferent and efferent fibers. Evidence suggests that altered VN signaling is linked to changes in the neuroimmune system, including microglia. Dysfunction of microglia, the resident innate immune cells of the brain, is associated with various neurodevelopmental disorders, including schizophrenia, attention deficit hyperactive disorder (ADHD), autism spectrum disorder (ASD), and epilepsy.

View Article and Find Full Text PDF

Adolescence is a developmental period marked by significant alterations to brain neurobiology and behavior. Adolescent nicotine use disrupts developmental trajectories and increases vulnerability to maladaptive drug-taking in adulthood. The mesolimbic dopamine (DA) system, including the nucleus accumbens core (NAc), mediates the reinforcing effects of nicotine.

View Article and Find Full Text PDF

Multiple gRNAs-assisted CRISPR/Cas12a-based portable aptasensor enabling glucometer readout for amplification-free and quantitative detection of malathion.

Anal Chim Acta

March 2025

College of New Energy Materials and Chemistry, Leshan Normal University, Leshan, Sichuan, 614000, PR China; Sichuan Province Key Laboratory of Natural Products and Small Molecule Synthesis, Leshan, Sichuan, 614000, PR China. Electronic address:

Background: The threat of toxic malathion residues to human health has always been a serious food safety issue. The CRISPR/Cas system represents an innovative detection technology for pesticide residues, but its application to malathion detection has not been reported yet. In addition, the multiple-guide RNA (gRNA) powered-CRISPR/Cas biosensor has the advantages of being fast, sensitive and does not require pre-amplification.

View Article and Find Full Text PDF

Electronic cigarettes for smoking cessation.

Cochrane Database Syst Rev

January 2025

Department of Health Promotion and Policy, University of Massachusetts, Amherst, MA, USA.

Background: Electronic cigarettes (ECs) are handheld electronic vaping devices that produce an aerosol by heating an e-liquid. People who smoke, healthcare providers, and regulators want to know if ECs can help people quit smoking, and if they are safe to use for this purpose. This is a review update conducted as part of a living systematic review.

View Article and Find Full Text PDF

Potential induction of apoptosis and acetylcholinesterase inhibition in Aedes mosquitoes by Streptomyces-derived ethyl acetate extract.

Trop Biomed

December 2024

Tropical Infectious Diseases Research and Education Centre (TIDREC), Higher Institution Centre of Excellence, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.

The use of Streptomyces secondary metabolites for mosquito control has recently received positive attention. Accordingly, this study was performed to elucidate the cellular, genomic and biochemical responses of Aedes mosquitoes to Streptomyces sp. KSF103 ethyl acetate (EA) extract, a mixture previously characterized for its potential bioactivity.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!