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Complications of Single-Use Flexible Ureteroscopy vs. Reusable Flexible Ureteroscopy: A Narrative Review.
Cureus
December 2024
Department of Urology, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU.
Urolithiasis, or kidney stones, is a painful condition that is becoming increasingly common worldwide. For many, the solution lies in a minimally invasive procedure called flexible ureteroscopy (fURS). This technique involves inserting a tiny, flexible scope into the urinary tract to break up and remove stones.
View Article and Find Full Text PDFNovel Collagenous Sponge Composites for Osteochondral Regeneration in Rat Knee Models: A Comparative Study of Keratin, Hydroxyapatite, and Combined Treatments.
Cureus
November 2024
Department of Orthopedics and Traumatology, Faculty of Medicine, University of Medicine and Pharmacy "Carol Davila", Bucharest, ROU.
This study aims to evaluate the osteoconductive and osteoinductive potential of novel composite collagenous sponges enriched with keratin (K), hydroxyapatite (HA), and their combination (K+HA) for osteochondral regeneration in rat knee models. By examining cell proliferation, mineralization, and vascularization, we aim to determine the regenerative effectiveness of these materials in promoting osteochondral repair, particularly in load-bearing joints like the knee. Addressing the problem of osteochondral defects (OCD), which lead to osteoarthritis-a condition characterized by pain and functional impairment-the hereby research evaluates these biomaterials for their potential to foster bone and cartilage repair, especially in load-bearing joints as the knee.
View Article and Find Full Text PDFAI-Based Analysis of Ziehl-Neelsen-Stained Sputum Smears for as a Screening Method for Active Tuberculosis.
Life (Basel)
November 2024
Department of Pathology, Colentina University Hospital, 21 Stefan Cel Mare Str., Sector 2, 020125 Bucharest, Romania.
Tuberculosis is the primary cause of death due to infection in the world. Identification of in sputum is a diagnostic test, which can be used in screening programs-especially in countries with a high incidence of tuberculosis-to identify and treat those persons with the highest risk of disseminating the infection. We previously developed an algorithm which is able to automatically detect mycobacteria on tissue; in particular, our algorithm identified acid-fast bacilli on tissue with 100% specificity, 95.
View Article and Find Full Text PDFContinuous and Dynamic Circulation of West Nile Virus in Mosquito Populations in Bucharest Area, Romania, 2017-2023.
Microorganisms
October 2024
Medical Entomology Laboratory, Cantacuzino National Military Medical Institute for Research and Development, 103 Splaiul Independenței, 050096 Bucharest, Romania.
Article Synopsis
- West Nile virus (WNV) is spreading to new areas in Europe, including Romania, due to climate change and human activities, with significant outbreaks recorded since 1996.
- A study focused on WNV strains in Romania from 2017 to 2023 analyzed viral sequences from mosquitoes, humans, and birds, highlighting the virus's ongoing circulation in the region.
- The research found lineage 2 WNV in both mosquito samples and human sera, identifying sub-lineages and clusters that reflect complex transmission patterns and evolutionary changes over time.
The Romanian Translation and Cultural Adaptation of the Early Arthritis for Psoriatic Patients (EARP) Questionnaire, Psoriasis Epidemiology Screening Tool (PEST), and Toronto Psoriatic Arthritis Screen 2 (ToPAS 2).
Clin Pract
October 2024
Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Background/objectives: Psoriasis is a chronic inflammatory condition mediated by the immune system with various manifestations. The increased prevalence of subclinical joint involvement has led to the development of early diagnostic methods for psoriatic arthritis, including several instruments that have been validated and used in clinical practice. The aim of this study was to perform the Romanian translation, cultural adaptation, and validation of three assessment tools: the Early Arthritis for Psoriatic Patients (EARP) Questionnaire, Psoriasis Epidemiology Screening Tool (PEST), and Toronto Psoriatic Arthritis Screen 2 (TOPAS 2), which are designed to evaluate early-stage arthritis in patients with psoriasis.
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