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The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis.
PLoS One
January 2025
School of Ophthalmology and Optometry, Wenzhou Medical University, Zhejiang, P. R. China.
Purpose: To evaluate the corneal biomechanical properties of phacoemulsification in the treatment of cataract patients.
Methods: Pertinent studies were searched in PubMed, EMBASE, Web of Science and clinicaltrials.gov.
Establishment of an Ex Vivo Human Corneal Endothelium Wound Model.
Transl Vis Sci Technol
January 2025
UCL Institute of Ophthalmology, University College London, London, UK.
Purpose: A human model able to simulate the manifestation of corneal endothelium decompensation could be advantageous for wound healing and future cell therapy assessment. The study aimed to establish an ex vivo human cornea endothelium wound model where endothelium function can be evaluated by measuring corneal thickness changes.
Methods: The human cornea was maintained in an artificial anterior chamber, with a continuous culture medium infusion system designed to sustain corneal endothelium and epithelium simultaneously.
Determinants of Human Corneal Mechanical Wave Dispersion for In Vivo Optical Coherence Elastography.
Transl Vis Sci Technol
January 2025
College of Optometry, University of Houston, Houston, TX, USA.
Purpose: To characterize frequency-dependent wave speed dispersion in the human cornea using microliter air-pulse optical coherence elastography (OCE), and to evaluate the applicability of Lamb wave theory for determining corneal elastic modulus using high-frequency symmetric (S0) and anti-symmetric (A0) guided waves in cornea.
Methods: Wave speed dispersion analysis for transient (0.5 ms) microliter air-pulse stimulation was performed in four rabbit eyes ex vivo and compared to air-coupled ultrasound excitation.
Artificial Cornea Substitute Based on Hydrogel Skeletons with Natural Stromal Hierarchical Structure and Extracellular Matrix for Sutureless Transplantation.
Adv Sci (Weinh)
January 2025
State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, 266071, China.
Corneal substitutes with structural and compositional characteristics resembling those of natural corneas have attracted considerable attention. However, biomimicking the complex hierarchical organization of corneal stroma is challenging. In this study, humanized corneal stroma-like adhesive patches (HCSPs) are prepared through a multi-step process.
View Article and Find Full Text PDFClassification and treatment approach of chemical burn associated Limbal stem cell deficiency: based on novel global consensus.
Int Ophthalmol
January 2025
Department of Ophthalmology, Ege University Medical Faculty Hospital, Ege University, 35100, Bornova, Izmir, Turkey.
Purpose: To evaluate the severity distribution of chemical burn-induced Limbal stem cell deficiency (LSCD) according to the novel global consensus classification and to compare the treatment approach, before and after the global consensus.
Methods: Medical records of 127 eyes of 109 patients with LSCD were included. LSCD stages were categorized according to the global consensus classification published by "International LSCD Working Group".
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