A 51-year-old patient with acute myelogenous leukemia, who was alloimmunized to platelets, failed to show adequate platelet increments after receiving transfusions of HLA grade A-identical platelets. Only platelets from an HLA grade B-matching donor gave high increments. Several crossmatching procedures were used to select platelet donors. A correlation was seen between in vitro tests and in vivo response. HLA typing has limitations in the selection of platelet-compatible donors.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
hla grade
8
platelet transfusion
4
transfusion therapy
4
therapy alloimmunized
4
alloimmunized patient
4
patient crossmatch
4
crossmatch procedures
4
procedures donor
4
donor selection
4
selection 51-year-old
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!