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Coral reefs can mitigate flood damages by providing protection to tropical coastal communities whose populations are dense, growing fast, and have predominantly lower-middle income. This study provides the first fine-scale, regionally modeled valuations of how flood risk reductions associated with hybrid coral reef restoration could benefit people, property, and economic activity along Florida and Puerto Rico's 1005 kilometers of reef-lined coasts. Restoration of up to 20% of the regions' coral reefs could provide flood reduction benefits greater than costs.

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Aim: Calcium silicate-based cements have been widely used in dentistry mainly due to their physicochemical and biological properties. Commercially available materials use radiopacifiers containing metals (bismuth, tantalum, tungsten and/or zirconium). To investigate volumetric changes, in vivo biocompatibility and systemic migration from eight commercially available materials, including powder/liquid and 'ready-to-use' presentations.

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Mutations disrupting the kinase domain of IKKα lead to immunodeficiency and immune dysregulation in humans.

J Exp Med

February 2025

Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, INSERM UMR 1163, Imagine Institute, University Paris Cité, Paris, France.

IKKα, encoded by CHUK, is crucial in the non-canonical NF-κB pathway and part of the IKK complex activating the canonical pathway alongside IKKβ. The absence of IKKα causes fetal encasement syndrome in humans, fatal in utero, while an impaired IKKα-NIK interaction was reported in a single patient and causes combined immunodeficiency. Here, we describe compound heterozygous variants in the kinase domain of IKKα in a female patient with hypogammaglobulinemia, recurrent lung infections, and Hay-Wells syndrome-like features.

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Background: To investigate the effect of rheumatoid arthritis (RA) on the incidence of peri-implantitis (PI) and peri-implant mucositis (PIM).

Methods: Radiographic and clinical chart reviews were conducted to measure the probing depth (PD), bleeding on probing, and marginal bone loss (MBL) around the implants to diagnose peri-implant diseases based on the 2017 workshop classification. Values were recorded at the baseline (T0) to the last available chart and radiograph (T1).

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<b>Introduction:</b> In the course of middle ear diseases, a disturbed influence of the system transmitting sound through the middle ear on the function of the inner ear is observed. The audiometric consequence of the disease process taking place in the middle ear is the shift in bone conduction (BC) thresholds, which is called pseudoperceptive hearing loss (the so-called Carhart effect). The natural process of aging of the hearing system (age-related hearing loss) means that the manifestation of the Carhart effect varies in different age groups.

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