A new method of tomography based on the principle of nuclear magnetic resonance (NMR-tomography) was used to determine the heart size in experimental animals. The study involved 25 rabbits and NMR-tomograms of their hearts were obtained both in situ and on the isolated heart. The results obtained were compared with the morphometric findings. It was found that the values of the heart size determined by NMR-tomograms as compared with the morphometric values both in situ and on the isolated heart were very similar, showing no statistical difference. When the tomographic findings were compared with the morphometric data, the correlation coefficient for the thickness of the left ventricle wall was 0.64; for the short axis of the left ventricle 0.55; for the perimeter of the left ventricle 0.70, and for the total size of the heart it equalled 0.98. It is inferred that NMR-tomography is quite adequate for taking the necessary measurements of the heart with sufficient precision.
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PLoS One
January 2025
Department of Anatomy, Nihon University School of Dentistry, Tokyo, Japan.
This study presents a novel method for creating customized brain slice matrices using Computer-Aided Design (CAD) and 3D printing technology. Brain Slice Matrices are essential jigs for the reproducible preparation of brain tissue sections in neuroscience research. Our approach leverages the advantages of 3D printing, including design flexibility, cost-effectiveness, and rapid prototyping, to produce custom-made brain matrices based on specific morphometric measurements.
View Article and Find Full Text PDFJ Evol Biol
January 2025
Laboratorio de Ecotono, Instituto de Investigaciones em Biodiversidad y Medioambiente (INIBIOMA), CONICET- Universidad Nacional del Comahue, San Carlos de Bariloche, Río Negro, Argentina.
Modularity and developmental (in)stability have the potential to influence phenotype production and, consequently, the evolutionary trajectories of species. Depending on the environmental factors involved and the buffering capacity of an organism, different developmental outcomes are expected. Cactophilic Drosophila species provide an established eco-evolutionary model with well-studied ecological conditions, making them ideal for studying these phenomena.
View Article and Find Full Text PDFJ Food Sci
January 2025
College of Food Science and Engineering, Henan University of Technology, Zhengzhou, China.
Flaxseed gum (FSG) has promising applications in the field of nano/microencapsulation for its biocompatibility and excellent physicochemical properties. In this study, FSG-based nano-microcapsules (FSG NPs) were prepared using high-speed shear homogenization combined with ultrasound for efficient encapsulation of secoisolariciresinol diglucoside (SDG). The particle size of FSG stands for nano-microcapsules (NP) was determined to be 336.
View Article and Find Full Text PDFJ Anat
January 2025
Center for Development Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, Washington, USA.
Geometric morphometrics is used in the biological sciences to quantify morphological traits. However, the need for manual landmark placement hampers scalability, which is both time-consuming, labor-intensive, and open to human error. The selected landmarks embody a specific hypothesis regarding the critical geometry relevant to the biological question.
View Article and Find Full Text PDFN Engl J Med
January 2025
From the Department of Medicine, University of Auckland, Auckland, New Zealand (M.J.B., Z.N., A.M., C.G., V.P., B.M., A.G., I.R.R., G.G., A.H.); the Department of Psychology, Stanford University, Stanford, CA (C.G.); and the Department of Radiology, Starship Hospital, Auckland, New Zealand (S.B.).
Background: Zoledronate prevents fractures in older women when administered every 12 to 18 months, but its effects on bone density and bone turnover persist beyond 5 years. Whether infrequent zoledronate administration would prevent vertebral fractures in early postmenopausal women is unknown.
Methods: We conducted a 10-year, prospective, double-blind, randomized, placebo-controlled trial involving early postmenopausal women (50 to 60 years of age) with bone mineral density T scores lower than 0 and higher than -2.
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