During postnatal development of rats under high-altitude conditions, the cardiac mass was enlarged as a result of cellular and intracellular hyperplastic processes. Under additional physical exercise the enlargement of the myocardial mass in high-altitude conditions resulted from the hypertrophy of muscle cells, i.e. from intracellular hyperplastic processes. The correlation between these two ways of the cardiac mass enlargement depends on the animals' age and the period of stay in mountains.
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Chem Biodivers
January 2025
Sofia University, Faculty of Biology, Plant Physiology, Dragan Tsankov 8, Sofia, BULGARIA.
Plantago atrata Hoppe is a high-altitude mountain plant exposed to harsh environmental factors. This study aims to elucidate the ecological, phytochemical and pharmacological characteristics of this lesser-known plantain. Despite nutrient-poor peat soil, the leaves of P.
View Article and Find Full Text PDFInt Arch Occup Environ Health
January 2025
Xining Centre for Disease Control and Prevention, Xining, Qinghai, 810000, China.
Background: The unique characteristics of air pollution in high-altitude regions may significantly influence the transmission and incidence of influenza. However, current research on this phenomenon is limited, and further investigation is urgently needed.
Methods: This study collected influenza outpatient data from Qinghai Province between January 1, 2016, and December 31, 2021.
Stem Cell Rev Rep
January 2025
Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Background: The hypobaric hypoxic atmosphere can cause adverse reactions or sickness. The purpose of this study was to explore the preventive effect and mechanism of human umbilical cord mesenchymal stem cells (hUC-MSCs) on acute pathological injury in mice exposed to high-altitude.
Methods: We pretreated C57BL/6 mice with hUC-MSCs via the tail vein injection, and then the mice were subjected to hypobaric hypoxic conditions for five days.
Monarch butterflies in North America migrate south each autumn, but the mechanisms that initiate their migratory flight remain incompletely understood. We investigated environmental, developmental, and genetic factors that contribute to directional flight by testing summer and autumn-generation monarchs in three flight simulators: two at ground level (with and without wind blockage) and a novel balloon-based system that raised butterflies 30 meters into the air. Monarchs reared under autumn-like conditions in a growth chamber during the summer were also tested to explore the influence of developmental cues.
View Article and Find Full Text PDFOxygen (Basel)
March 2025
Centro de Investigación en Medicina de Altura (CIMA), Facultad de Medicina Humana, Universidad de San Martín de Porres, Lima 15001, Peru.
Previous studies indicate that individuals at high altitudes have a lower pain threshold than those living at sea level. This study evaluates the differences in pain perception among young people living at an altitude of 3800 m and after acute exposure to a severe hypoxic environment at more than 5100 m. Fourteen people (BMI of 22.
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