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Integrating High-intensity Focused Ultrasound with Chemotherapy for the Treatment of Invasive Hydatidiform Mole in Reproductive-age Women.
Gynecol Minim Invasive Ther
July 2024
Department of Gynecological, Chengdu Focused Ultrasound Hospital, Chengdu, China.
Article Synopsis
- Invasive hydatidiform mole is a dangerous growth that can happen in women of reproductive age, and it can lead to serious health problems.
- A 24-year-old Chinese woman with no previous pregnancies had ongoing bleeding after a medical procedure, and doctors found abnormal growths in her uterus.
- She was treated with chemotherapy and a special ultrasound technique, which helped improve her condition and showed positive results in follow-up exams.
Diandric triploid partial mole versus digynic nonmolar triploidy: is morphological assessment sufficient for the diagnostic distinction?
Histopathology
December 2024
Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
Aims: Diagnostic separation of diandric triploid gestation, i.e. partial mole from digynic triploid gestation, is clinically relevant, as the former may progress to postmolar gestational trophoblastic neoplasia.
View Article and Find Full Text PDFMixed Gestational Trophoblastic Tumors-Challenging Clinicopathological Presentations.
Int J Gynecol Pathol
January 2025
Center for the Precision Medicine of Trophoblastic Disease, Department of Pathology, Yale School of Medicine, New Haven, Connecticut.
Mixed gestational trophoblastic tumors are exceptionally rare and have variable clinicopathological presentations. We report 3 such tumors with different combinations of choriocarcinoma (CC), placental site trophoblastic tumor (PSTT), and epithelioid trophoblastic tumor (ETT). The patients' age ranged from 38 to 44 years.
View Article and Find Full Text PDFHeterotopic pregnancy: a case report of intrauterine hydatidiform mole with tubal pregnancy.
J Int Med Res
June 2024
Department of Obstetrics and Gynecology, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, China.
We herein report a rare case of simultaneous intrauterine molar pregnancy and tubal pregnancy. A woman of childbearing age who had never been pregnant underwent an ultrasound examination 70 days after the onset of menopause. She had a history of ovulation induction.
View Article and Find Full Text PDFMorphology combined with D-DISH ploidy analysis to diagnose partial hydatidiform mole: an evaluation audit using molecular genotyping.
J Clin Pathol
August 2024
Pregnancy Loss Research Group, Department of Obstetrics & Gynaecology, University College Cork, Cork, Ireland.
Aims: A hydatidiform mole (HM) is classified as complete (CHM) or partial (PHM) based on its morphology and genomic composition. Ancillary techniques are often required to confirm a morphologically suspected PHM diagnosis. This study sought to evaluate the clinical accuracy of PHM diagnosis using morphological assessment supported by dual-colour dual-hapten in situ hybridisation (D-DISH) ploidy determination.
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