This clinical and laboratory investigation is devoted to the study of the levels and correlation between the total gonadotropins and antigonadotropin factors excreted in the urine of 10-18-year-old girls. There was found a correlation between the excretion of total gonadotropins and the concentration of their inhibitors. Periods of the greatest fall of the antigonadotropin level corresponded to the peaks of gonadotropin activity.

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