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A Residual Marker of Cognitive Reserve Is Associated with Resting-State Intrinsic Functional Connectivity Along the Alzheimer's Disease Continuum.
J Alzheimers Dis
April 2023
Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Germany.
Background: Cognitive reserve (CR) explains inter-individual differences in the impact of the neurodegenerative burden on cognitive functioning. A residual model was proposed to estimate CR more accurately than previous measures. However, associations between residual CR markers (CRM) and functional connectivity (FC) remain unexplored.
View Article and Find Full Text PDF[Weaving with Ti-Sage].
Soins Gerontol
August 2022
Centre Ker Heol, 97 rue de Belgique, 56100 Lorient, France.
The Ti-Sage mobile geronto-psychiatry team provides semi-emergency care in the Sud Bretagne public mental health establishment sector. The system favours fluidity and responsiveness. Requests can be made by telephone without filling in a form.
View Article and Find Full Text PDFDissecting Digital Card Games to Yield Digital Biomarkers for the Assessment of Mild Cognitive Impairment: Methodological Approach and Exploratory Study.
JMIR Serious Games
November 2021
e-Media Research Lab, Katholieke Universiteit Leuven, Leuven, Belgium.
Background: Mild cognitive impairment (MCI), the intermediate cognitive status between normal cognitive decline and pathological decline, is an important clinical construct for signaling possible prodromes of dementia. However, this condition is underdiagnosed. To assist monitoring and screening, digital biomarkers derived from commercial off-the-shelf video games may be of interest.
View Article and Find Full Text PDFCognitive profiles of patients with mild cognitive impairment due to Alzheimer's versus Parkinson's disease defined using a base rate approach: Implications for neuropsychological assessments.
Alzheimers Dement (Amst)
September 2021
Department of Medical Psychology Neuropsychology & Gender Studies; Center for Neuropsychological Diagnostics and Intervention (CeNDI) Faculty of Medicine and University Hospital Cologne, University of Cologne Cologne Germany.
Article Synopsis
- - The study focuses on comparing cognitive profiles of patients with mild cognitive impairment related to Alzheimer's disease (AD-MCI) and Parkinson's disease (PD-MCI), noting that large studies on this topic are limited.
- - Data from two large cohort studies were analyzed using a common diagnostic approach, revealing that AD-MCI patients performed worse on memory and language tests, while PD-MCI patients struggled more with executive tasks involving set-shifting.
- - The results indicate that a specific neuropsychological test battery can effectively differentiate between AD-MCI and PD-MCI, suggesting that clinical assessments should encompass a wide range of cognitive areas to identify potential changes.
[Complex treatment of severe mental illnesses in old age].
Nervenarzt
September 2021
Professur Sozial- und Präventivmedizin, Universität Potsdam, Potsdam, Deutschland.
Background: The needs for assistance, support and treatment of older people with severe mental illnesses (SMI) are very high and linked to additional age-associated somatic diseases and impairments. Old people prefer to live independently in their own homes and to receive necessary treatment and support there; however, a resettlement in a residential nursing home is often necessary due to a lack of alternatives.
Objective: What is the current treatment reality in Germany for old people with SMI in their own homes and in residential nursing homes? How can coercive measures in this context be prevented?
Methods: Selected results from the scientific literature on psychogeriatric care models in older people with SMI are summarized and discussed.
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