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Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles.
J Nanobiotechnology
January 2025
Department of Dermatology and Venereology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Background: Both oxidative stress and autoimmune responses play crucial roles in the development of vitiligo. Under oxidative stress, the apoptotic melanocytes expose self-antigens and release high mobility group box 1 (HMGB1), triggering autoimmune activation and recruiting CD8 T cells. This process further leads to the destruction of melanocytes, resulting in the lack of melanin granules.
View Article and Find Full Text PDFWhose autonomy support is more effective in promoting exercise adherence in higher vocational college students - based on self-determined theory.
BMC Public Health
January 2025
Faculty of Physical Education and Health, Lin yi University, Lin yi, 276006, China.
Objective: Based on the self-determination theory, the three types of autonomy support of parents, teachers and peers as a whole were included in the same research system to explore their effects on exercise adherence of higher vocational college students and their internal mechanisms.
Methods: The study used the exercise autonomy support scale, autonomous motivation scale and exercise adherence scale to construct and test the hypothesised pathways for promoting exercise adherence among students in higher vocational college. Using the data obtained from a survey of 436 higher vocational college students as the unit of analysis, and taking into account the variable of students' self-determined motivation.
Influence of different polymeric materials of implant and attachment on stress distribution in implant-supported overdentures: a three-dimensional finite element study.
BMC Oral Health
January 2025
Department of Prosthetic Dentistry, Biomaterials Division, Faculty of Dentistry, King Salman International University, El Tur, South Sinai, Egypt.
Purpose: Investigating high performance thermoplastic polymers as substitutes to titanium alloy, in fabrication of implants and attachments to support mandibular overdenture, aiming to overcome stress shielding effect of titanium alloy implants. AIM OF STUDY: Assessment of stress distribution in polymeric prosthetic components and bone around polymeric implants, in case of implant-supported mandibular overdenture.
Materials And Methods: 3D finite element model was established for mandibular overdenture, supported bilaterally by two implants at canine region, and retained by two ball attachments.
Change point detection in brucellosis time series from 2010 to 2023 in Xinjiang China using the BEAST algorithm.
Sci Rep
January 2025
College of Medical Engineering and Technology, Xinjiang Medical University, Urumqi, 830017, China.
Brucellosis is a significant global challenge, but there has been a lack of epidemiological studies on brucellosis in Xinjiang from a change point perspective. This study aims to bridge this gap by employing sequence decomposition and identifying significant change points, with datasets sourced from the Xinjiang Disease Prevention and Control Information System. This study employed the BEAST algorithm to decompose the brucellosis time series in Xinjiang from 2010 to 2023, while simultaneously identifying change points in the decomposed seasonal and trend components.
View Article and Find Full Text PDFAdaptive hybrid virtual inertia controller for PMSG-based wind turbine based on fuzzy logic control.
Sci Rep
January 2025
Electrical Power and Machines Department, Faculty of Engineering, Ain Shams University, Ain Shams, Egypt.
The integration of renewable energy sources into microgrids presents some challenges due to the decreased system overall inertia associated with the presence of converter -based sources. To overcome this issue and to enhance the system inertia, various concepts for virtual inertial control have been proposed in the literature. However, the concept of improving the system frequency through wind turbines has gained widespread acceptance.
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