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Localized light chain amyloidosis of the stomach that regressed after eradication of Helicobacter pylori over 15 years of follow-up: a case report and new hypothesis.
Clin J Gastroenterol
January 2025
Department of Gastroenterology, Saiseikai Kanazawa Hospital, Ni-13-6 Akatsuchimachi, Kanazawa, Ishikawa, 920-0353, Japan.
Localized light chain amyloidosis is considered to be a plasmacytic B-cell lymphoproliferative disorder caused by antigenic induction. A hypothesis has been proposed that antigen-induced local plasmacytic B cells produce amyloidogenic proteins that are processed into amyloid fibrils in giant cells leading to amyloid fibril deposition. However, the inciting antigen exposure or immune response that signals plasmacytic B-cell infiltration, activation, and selection, is unknown.
View Article and Find Full Text PDFSolitary Giant Primary Gastric Plasmacytoma Mimicking Gastric Adenocarcinoma In Situ.
Cureus
September 2024
Hematology and Oncology, Hospital Militar Central, Bogotá, COL.
A solitary extraosseous plasmacytoma is a rare type of plasma cell neoplasm. Its occurrence in the stomach is particularly unusual and can easily be mistaken for more common types of tumors. We describe a case involving a solitary extraosseous plasmacytoma in a patient who experienced weight loss as the sole symptom.
View Article and Find Full Text PDFExtraosseous Plasmacytomas: A Radiologist's Perspective-A Narrative Review of the Literature.
Diagnostics (Basel)
August 2024
Department of Radiology, General University of Patras, 61000 Patras, Greece.
Article Synopsis
- * EPs can appear in various body parts, including the lungs, breasts, and abdominal organs, making them tough to diagnose due to their similar imaging characteristics to other conditions.
- * The review highlights the importance of imaging for detecting EPs, but emphasizes that a histological confirmation is essential for an accurate diagnosis, especially for patients with a history of multiple myeloma, as timely diagnosis can greatly improve
18 F-FAPI-04 PET/CT in a Case of Primary Gastric Plasmacytoma.
Clin Nucl Med
July 2024
From the Department of Nuclear Medicine, General Hospital of Ningxia Medical University.
Primary plasmacytoma of the stomach is very rare. We describe contrast-enhanced CT and 18 F-FAPI-04 PET/CT findings in a patient with primary gastric plasmacytoma and Helicobacter pylori infection. The gastric tumor appeared as a large hypervascular polypoid mass on contrast-enhanced CT and showed intense 18 F-FAPI-04 uptake with SUV max of 11.
View Article and Find Full Text PDFRelapsed multiple myeloma with gastric and pancreatic extramedullary plasmacytomas.
J Formos Med Assoc
April 2023
Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. Electronic address:
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