Minocycline hydrochloride hepatotoxic effect occurred in one patient. Unlike the usual histologic features of tetracycline-induced hepatic injury, fatty metamorphosis was predominantly macrovesicular . The patient recovered when drug therapy was withdrawn. Close observation of liver function variables is recommended in patients treated with high parenteral doses of minocycline, particularly in cases of pregnancy or renal disease.

Download full-text PDF

Source

Publication Analysis

Top Keywords

hepatic injury
8
acute hepatic
4
injury associated
4
associated minocycline
4
minocycline minocycline
4
minocycline hydrochloride
4
hydrochloride hepatotoxic
4
hepatotoxic occurred
4
occurred patient
4
patient usual
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!