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Malaria is highly endemic and unstable in the central Highlands plateau of Madagascar. The infection is seasonally transmitted by Anopheles funestus and An. arabiensis.

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Laboratory experiments have brought the authors to a conclusion on the efficacy of B. thuringiensis and B. sphaericus-based insecticides in salty water mosquito breeding sites.

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The optimal bactoculicide/sphaerolarvicide ratio in combination using against Aedes aegypti larvae was established in laboratory by selection. The field trials of the selected BS/BT sample containing the ingredients in titer: bactoculicide-83, sphaerolarvicide-17 were conducted in the arid area of Central Asia. With 1 g/m2, complete mortality of Culex, Aedes and Anopheles larvae was obtained with the residual larvicidal action of 15 days.

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