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Impact of a lagoon with high anthropic activity on a World Heritage Site.
Environ Monit Assess
January 2025
Department of Earth Science, University of Bizerte-FSB, University of Carthage, 7120, Bizerte, Tunisia.
The Ichkeul-Bizerte Lagoon Complex (IBLC), a critical ecosystem for local biodiversity, faces a pressing threat due to climate change and severe pollution. Despite past conservation efforts, pollution persists, particularly in the Bizerte Lagoon. This study investigated the impact of water dynamics and climatic conditions on heavy metal contamination in the IBLC's sediments.
View Article and Find Full Text PDFThe Influence of Sex, Fitness, BMI, and Cardiovascular Risk Factors on Cerebral Blood Velocity Responsiveness to Graded Exercise Testing in Middle-Aged Adults.
J Gerontol A Biol Sci Med Sci
December 2024
GENUD Toledo Research Group, Faculty of Sport Sciences, University of Castilla-La Mancha, Toledo, Spain.
Mean middle cerebral artery velocity (MCAv) and the pulsatility index (PI), at rest and in response to exercise, are important markers of cerebrovascular health status in middle-aged adults, when vascular decline assumes substantial relevance. Thus, this study aimed to describe and compare the responses of MCAv and PI to incremental exercise. Two hundred and forty-eight volunteers (50-58 years, 55% women) completed a ramp test on a cycle-ergometer.
View Article and Find Full Text PDFEffect of a Medication Adherence Education Intervention on Clinical Outcomes in Adults with Type 2 Diabetes Mellitus: A Randomized Controlled Trial Study.
Endocr Metab Immune Disord Drug Targets
January 2025
Mohammad Asghari Jafarabadi: Professor of Biostatistics, Cabrini Research, Cabrini Health, VIC 3144, Australia; School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, VIC 3800, Australia; Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: Low adherence to Oral Antidiabetic Drugs (OADs) in adults with Type 2 Diabetes Mellitus (T2DM) leads to complications, death, and increased healthcare costs.
Objective: This study aimed to evaluate the effectiveness of medication adherence education interventions for the clinical outcomes of adults with T2DM.
Materials And Methods: Seventy adults with T2DM from an outpatient clinic in the City of Ardabil, Iran, participated in this study.
A Single-Center Retrospective Cohort Study of Biopterin Metabolism Disorders in the United Arab Emirates.
JIMD Rep
January 2025
Genetic and Metabolic Division, Pediatrics Department Tawam Hospital Al Ain UAE.
Background: Tetrahydrobiopterin (BH4) deficiencies comprise a group of five neurometabolic disorders caused by five genetic defects responsible for BH4 biosynthesis and regeneration. Their global prevalence remains unknown, and variance exists among different countries.
Aims: To describe clinical, biochemical, molecular genetic data and follow-up of patients with BH4 deficiency seen in Tawam Hospital.
The effects of aerobic exercise and heat stress on the unbound fraction of caffeine.
Front Physiol
January 2025
Human Physiology Research Unit, Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.
Introduction: The fraction of drug circulating in the blood that is not bound to plasma proteins ( ) is considered pharmacologically active since it readily binds to its receptor. evidence suggests that changes in temperature and pH affect the affinity of drug binding to plasma proteins, resulting in changes in . In light of the well-established effects of exercise on body temperature and blood pH, we investigated whether an increase in blood temperature and decrease in pH facilitated through passive heating and exercise translated to a change in the of caffeine.
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