A follow-up study (in 6.4 years) of a group of men aged 40-49 years (an average of 46.9) and engaged in strenuous mental work detected a large number of coronary heart disease (CHD) patients (28.9%) which exceeds the CHD incidence in the corresponding age groups of population threefold. Essential hypertension, hyperlipoproteinemia, smoking and stressful situations were shown to be valuable predictors of CHD. One of the major risk factors of CHD in the 40-49-year-old men studied was intensity of mental work.

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