Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1109/TBME.1984.325366 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Generalized, sublethal damage-based mathematical approach for improved modeling of clonogenic survival curve flattening upon hyperthermia, radiotherapy, and beyond.
Phys Med Biol
January 2025
OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Helmholtz-Zentrum Dresden - Rossendorf, Dresden, Sachsen, 01307, GERMANY.
Mathematical modeling can offer valuable insights into the behavior of biological systems upon treatment. Different mathematical models (empirical, semi-empirical, and mechanistic) have been designed to predict the efficacy of either hyperthermia (HT), radiotherapy (RT), or their combination. However, mathematical approaches capable of modeling cell survival from shared general principles for both mono-treatments alone and their co-application are rare.
View Article and Find Full Text PDFActivation of the nucleus accumbens promotes place preference and counteracts stress-induced hyperthermia.
iScience
November 2024
Department of Physiology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Positive affect promotes mental health and physical well-being, which may involve modifications in the autonomic nervous system activity. Here, we examine, using chemogenetic techniques, the effects of nucleus accumbens (NAc) activation on affect and body temperature regulation as a proxy of autonomic function. A conditioned place preference test revealed that nucleus accumbens activation induced positive affect.
View Article and Find Full Text PDFStimulant medications effects in heat-related illness in ADHD patients: a large database study.
Front Psychiatry
December 2024
Department of Internal Medicine, Howard University, Washington, DC, United States.
Introduction: Attention Deficit Hyperactivity Disorder (ADHD), a prevalent neurodevelopmental disorder affecting a significant portion of the population, is commonly managed with stimulant medications. These medications, while effective, have been associated with thermoregulatory dysfunction and an increased risk of heat-related adverse events. The current study sought to compare the incidence of such events in ADHD patients receiving stimulant medications with those not on these treatments.
View Article and Find Full Text PDFInjectable, self-healing and phase change nanocomposite gels loaded with two nanotherapeutic agents for mild-temperature, precise and synergistic photothermal-thermodynamic tumor therapy.
J Colloid Interface Sci
December 2024
School of Materials Science and Engineering, Key Laboratory of Advanced Civil Materials of Ministry of Education, Tongji University, Shanghai 201804, PR China. Electronic address:
Hyperthermia has emerged as a popular treatment option due to its high efficacy and seamless integration with other therapeutic approaches. To enhance treatment outcomes, hydrogels loaded with photothermal agents and activated by near-infrared (NIR) light for localized tumor therapy have attracted considerable attention. This approach minimizes drug dosage and mitigates the adverse effects of systemic drug delivery on healthy tissues.
View Article and Find Full Text PDFA pre-clinical MRI-guided all-in-one focused ultrasound system for murine brain studies.
Sci Rep
January 2025
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
This paper describes the design and initial proof-of-concept of a single pre-clinical transcranial focused ultrasound (FUS) system capable of performing histotripsy (mechanical ablation), hyperthermia, blood-brain barrier opening (BBBO), sonodynamic therapy, or neuromodulation in a murine brain. We have termed it the All-in-One FUS system for murine brain studies, which is the first FUS system of its kind. The 1.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!