Cell nuclear deoxyribonucleic acid (DNA) content was microspectrophotometrically determined in 35 cases of mucosal and submucosal carcinoma of the esophagus. DNA distribution pattern was classified into types I, II, III, and IV, according to the degree of dispersion on the DNA histogram, in the order of wider distribution. Patients with types I and II (relatively regular in DNA distribution) had an uneventful postoperative course and no recurrence, whereas 3 of 15 (20%), and 5 of 9 (55.6%) with type III and type IV, respectively (widely scattered DNA distribution), died following a recurrence. Cytophotometric DNA analysis of the cancer cells reflected well the outcome in patients with esophageal carcinoma. These results suggest the potential usefulness of cytophotometric DNA analysis for assessing the prognosis, even in the early stage of esophageal carcinoma.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/1097-0142(19840615)53:12<2683::aid-cncr2820531220>3.0.co;2-c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Irrigation affects characteristics of narrow-leaved lupin (Lupinus angustifolius L.) seeds.
Planta
June 2019
Department of Cytophysiology, Faculty of Biology and Environmental Protection, University of Łódź, ul. Pomorska 141/143, 90-236, Lodz, Poland.
While plant irrigation usually increases yield, irrigation also affects seed characteristics with respect to endoreplication level, chemical composition, number of carbonyl bands, and cuticular wax profiles. Seeds of sweet varieties of the narrow-leaved lupin have good nutritional properties; however, these plants are sensitive to water deficit. Irrigation improves lupin yield, but can affect seed characteristics.
View Article and Find Full Text PDFMorphology, morphometry and chromatin distribution in llama sperm nuclei.
Reprod Domest Anim
April 2018
Facultad de Ciencias Veterinarias, Instituto de Investigación y Tecnología en Reproducción Animal (INITRA), Cátedra de Física Biológica, Ciudad Autónoma de Buenos Aires, Universidad de Buenos Aires, Buenos Aires, Argentina.
The objectives of this study were as follows: (i) to describe and evaluate the frequencies of different morphologies of llama sperm nuclei, (ii) to determine morphometric values of nuclear parameters, (iii) to describe and estimate the frequencies of different classes of chromatin distribution and (iv) to measure haploid DNA content and analyse its nuclear distribution. The study was performed using ejaculates collected from seven males, and sperm nuclei were stained with the Feulgen reaction. Normal morphology ranged from 78.
View Article and Find Full Text PDFCharacterization of the atypical lymphocytes in African swine fever.
Vet World
July 2016
Laboratory of Cell Biology and Virology, Institute of Molecular Biology of NAS, 7 Hasratyan St, 0014 Yerevan, Armenia.
Aim: Atypical lymphocytes usually described as lymphocytes with altered shape, increased DNA amount, and larger size. For analysis of cause of genesis and source of atypical lymphocytes during African swine fever virus (ASFV) infection, bone marrow, peripheral blood, and in vitro model were investigated.
Materials And Methods: Atypical lymphocytes under the influence of ASFV were studied for morphologic, cytophotometric, and membrane surface marker characteristics and were used in vivo and in vitro models.
DNA cytophotometric and histological analysis of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced precancerous lesions of the bladder urothelium.
J Cancer Res Clin Oncol
June 2016
Clinic and Policlinic of Urology, Hufelandstraße 55, 45147, Essen, Germany.
Purpose: The morphology of experimentally induced urinary bladder precancerous lesions has been differentially interpreted in the literature. Here, we aimed to describe the development of precancerous lesions of the urothelium histologically and by DNA cytophotometric analysis.
Methods: We induced precancerous lesions of the urothelium in 60 Wistar rats with 0.
Glycogen content in hepatocytes is related with their size in normal rat liver but not in cirrhotic one.
Cytometry A
April 2016
Laboratory of Cellular Pathology, Institute of Cytology of the Russian Academy of Sciences, Saint Petersburg, Russia.
Background & Aims: Hepatocytes differ from one another by the degree of the ploidy, size, position in the liver lobule, and level of the DNA-synthetic processes. It is believed, that the cell size exerts substantial influence on the metabolism of the hepatocytes and the glycogen content in them. The aim of the present study was to test this hypothesis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!