380 B. glabrata infected with 1 miracidium of S. mansoni produced 87 positive snails (22,9%), 38 of which sending out male cercariae and 49 female cercariae. The snails belonged to 3 experimental series kept at 27 degrees and 24 degrees C for 15 weeks under continuous lighting. There was no difference between the proportions of both sexes. The survival of the positive snails was favoured by the male sex. The shedding of female cercariae was greater than shedding of male. During those 15 weeks, the cercarial shedding of both sexes showed large and recurring changes. A certain correlation seems to exist between the sex of cercariae, the abundance and the frequency of cercarial shedding, and the longevity of the parasitized snails. All those factors could take a part in the epidemiology of the schistosomiasis.
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Indian J Pathol Microbiol
January 2025
Department of Pathology, Beijing Geriatric Hospital, Beijing, China.
Background: Investigation of a potential prognostic marker expressed in non-small cell lung cancer (NSCLC) can help patients benefit from new target therapeuticmodalities.
Aims: To study the expression and correlation of P53 protein and epithelial-mesenchymal transition (EMT) related makers in NSCLC.
Materials And Methods: 32 cases were selected for immunohistochemistry analysis to evaluate the expression of P53 and EMT-related makers.
Molecules
January 2025
Institute of Organic Chemistry with Center for Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Many biologically active compounds have been identified in the mucus of the garden snail , which are effective in the treatment of several diseases such as cancer, ulcers, wounds, etc. The incorporation of these compounds into the green synthesis of copper nanoparticles (CuONPs-Muc) was demonstrated in our previous study. Based on the synergistic effect of two reducing agents- snail mucus and ascorbic acid (AsA)-on CuSO.
View Article and Find Full Text PDFPol J Pathol
January 2025
Department of Biology, Faculty of Dentistry, Gazi University, Ankara, Turkey.
The role of cancer stem cells (CSC) in oral cancer is widely accepted. Yet, the existence of CSC in dysplastic tissue and the molecular pathways of progression from dysplasia to malignancy remain to be explored. Our retrospective study aimed to analyze the presence of CSC in oral epithelial dysplasia and oral squamous cell carcinoma (OSCC) concerning two epithelial-mesenchymal transition markers: Snail and E-cadherin.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
June 2024
Anqing Municipal Institute of Schistosomiasis Control, Anqing, Anhui 246001, China.
Objective: To investigate the distribution of snails in different water systems in Anqing City from 2016 to 2022, so as to provide insights into snail control in the city.
Methods: Snail survey data and distribution of water systems in snail-infested environments were collected from schistosomiasis-endemic areas of Anqing City from 2016 to 2022. The vector maps of towns and water systems in Anqing City were downloaded from National Geomatics Center of China.
J Cell Mol Med
January 2025
Department of Ophthalmology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, P. R. China.
The activation of the human interferon-inducible protein X (IFIX) isoform is associated with maintaining a stable cytoskeleton and inhibiting epithelial-mesenchymal transition (EMT). However, the mechanisms and pathways underlying IFIX-mediated oncogenesis are not well understood. In this study, we investigated the effects of IFIX overexpression and knockdown in CAL-27 and SCC-25 oral squamous cell carcinoma (OSCC) cells.
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