The work is based on observations over 168 patients with infectious-allergic myocarditis. The principal clinical, instrumental-laboratory, and morphologic criteria of this disease are discussed. The contractile function of the myocardium and central hemodynamics were studied. Intravital puncture biopsy of the myocardium was employed for the first time in this disease. Clinico-morphologic variants of infectious-allergic myocarditis are distinguished.
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Vopr Kurortol Fizioter Lech Fiz Kult
July 2019
M.F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia.
Introduction: Myocarditis is one of the most urgent and in many respects unresolved problems in cardiology. The situation is further aggravated by the ever increasing incidence of the of disease. The lack of knowledge about myocarditis etiology and pathogenesis creates a number of difficulties for the choice of the adequate treatment strategies.
View Article and Find Full Text PDFMorphological and functional changes of the myocardium were studied in 40 patients with candidiasis and attempt to establish morphological criteria of fungal myocarditis was undertaken. Retrospective analysis of autopsy material showed that myocardial involvement in candidiasis was possible and was not as rare as it had been accepted. Clinical symptomatology was not always similar to that of classical infectious-allergic myocarditis.
View Article and Find Full Text PDFTotal contractility reserve (TCR) and role of TCR in prediction of dilated cardiomyopathy (DCM) were evaluated in patients with infectious allergic myocarditis (IAM) by means of stress-echocardiography with dobutamine. Systolic function of the left ventricle (LV) appeared activated in different degree in relatively equal baseline low levels of LV contractility. IAM patients with reduced reserve of TCR are characterized by low increment of LV contractility under stress test and frequent onset of DCM.
View Article and Find Full Text PDFKlin Med (Mosk)
January 1998
Odintsovskaia tsentral'naia bol'nitsa, Moskovskaia oblast'
The courses and outcomes of infectious-allergic myocarditis (IAM) were analysed in 96 IAM patients to elucidate prognostically essential factors. These appeared to be: combination of left ventricular dilation with disturbed repolarization and ventricular rhythm, left atrial dilation, QRS index, a number of echocardiographic indices. There are some minor factors which in certain combination can provide additional prognostic information as regards IAM course and outcome.
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