Nerve section is followed by a reduction of motor and sensory conduction velocity in the proximal segment of the injured nerve. This reduction of velocity is associated with retrograde changes in fiber size. If reinnervation does not occur within the next 1 1/2--2 years, retrograde degeneration of nerve fibers results, and the amplitude of the evoked nerve potential in the proximal segment of the injured nerve decreases. This retrograde degeneration is probably significant in view of the poor results frequently obtained after nerve transplantation which is carried out too late.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF00316573 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mitochondria and its epigenetic dynamics: Insight into synaptic regulation and synaptopathies.
Funct Integr Genomics
January 2025
National Agri-Food and Biomanufacturing Institute, Sector-81, SAS Nagar, Knowledge City, Punjab, India.
Mitochondria, the cellular powerhouses, are pivotal to neuronal function and health, particularly through their role in regulating synaptic structure and function. Spine reprogramming, which underlies synapse development, depends heavily on mitochondrial dynamics-such as biogenesis, fission, fusion, and mitophagy as well as functions including ATP production, calcium (Ca) regulation, and retrograde signaling. Mitochondria supply the energy necessary for assisting synapse development and plasticity, while also regulating intracellular Ca homeostasis to prevent excitotoxicity and support synaptic neurotransmission.
View Article and Find Full Text PDFRNA Metabolism and the Role of Small RNAs in Regulating Multiple Aspects of RNA Metabolism.
Noncoding RNA
December 2024
Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
RNA metabolism is focused on RNA molecules and encompasses all the crucial processes an RNA molecule may or will undergo throughout its life cycle. It is an essential cellular process that allows all cells to function effectively. The transcriptomic landscape of a cell is shaped by the processes such as RNA biosynthesis, maturation (RNA processing, folding, and modification), intra- and inter-cellular transport, transcriptional and post-transcriptional regulation, modification, catabolic decay, and retrograde signaling, all of which are interconnected and are essential for cellular RNA homeostasis.
View Article and Find Full Text PDFBile Duct Injury During Laparoscopic Cholecystectomy: Has Anything Changed in 32 Years of Queensland Experience?
Cureus
December 2024
Hepatopancreatobiliary Surgery, Princess Alexandra Hospital, Brisbane, AUS.
Background Bile duct injury (BDI) is a serious complication of laparoscopic cholecystectomy (LC). Large studies report an incidence of 0.08%-0.
View Article and Find Full Text PDFPurpose: Previous studies have shown that subtrochanteric femoral fractures treated with intramedullary nails might lead to varus-procurvatum malalignment. Similar results have been reported when using antegrade intramedullary lengthening nails (ILNs). The purpose of our study is to examine if antegrade telescoping intramedullary lengthening nails lead to varus-procurvatum malalignment of the proximal femur and what are possible predictors of that shift.
View Article and Find Full Text PDFEfficacy and influencing factors of percutaneous transhepatic cholangiography and biliary drainage in malignant obstructive jaundice patients.
Am J Transl Res
December 2024
Department of Interventional Radiology, The Second Affiliated Hospital of Anhui Medical University Heifei 230001, Anhui, China.
Objectives: To analyze the efficacy and influencing factors of percutaneous transhepatic cholangiography and biliary drainage (PTCD) in patients with malignant obstructive jaundice (MOJ).
Methods: The study included 151 MOJ patients admitted from January 2021 to January 2024. Seventy patients in the control group received endoscopic retrograde cholangiopancreatography (ERCP), while 81 patients in the research group underwent PTCD.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!