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Comparison between a new device for the semen quality analysis and the manual microscopic evaluation in a not specialistic clinical laboratory.
Adv Lab Med
December 2024
Clinical Biochemistry Laboratory, Provincial Hospital of Bolzano (SABES-ASDAA), Bolzano, Italy.
Objectives: Semen analysis investigates different parameters of human semen with a high relevance in fertility workup, confirmation of sterility by post vasectomy, in pathologies follow-up such as varicocele and in all cases where sperm preservation is required. Manually seminal fluid examination is characterized by poor reproducibility. Aim of this study was to evaluate the performance of an automatic device in semen analysis by comparing its results with those obtained with the manual microscopy.
View Article and Find Full Text PDFPost-Vasectomy Semen Analysis: What's All the Fuss about?
Diagnostics (Basel)
October 2024
Global Andrology Forum, Moreland Hills, OH 44022, USA.
Article Synopsis
- *Societal changes have led to more younger, childless men choosing vasectomies, highlighting the need for better PVSA compliance and patient education regarding the time it takes for the procedure to become fully effective.
- *There are inconsistencies in PVSA practices, with recent developments like home testing kits raising questions about their reliability, indicating a need for standardized protocols across healthcare systems.
Purpose Artificial intelligence (AI) has rapidly gained popularity with the growth of ChatGPT (OpenAI, San Francisco, USA) and other large-language model chatbots, and these programs have tremendous potential to impact medicine. One important area of consequence in medicine and public health is that patients may use these programs in search of answers to medical questions. Despite the increased utilization of AI chatbots by the public, there is little research to assess the reliability of ChatGPT and alternative programs when queried for medical information.
View Article and Find Full Text PDFGood practice in laboratory diagnostic andrology: Association of Reproductive and Clinical Scientists guidelines 2024.
Reprod Biomed Online
December 2024
https://www.rbmojournal.com/article/S1472-6483(24)00291-8/fulltext.
These guidelines update and clarify items relating to diagnostic andrology in the 2012 Association of Biomedical Andrologists Laboratory Andrology Guidelines for Good Practice Version 3. The main change separates diagnostic and therapeutic andrology into individual documents; post-vasectomy semen analysis still references the 2016 guideline. These guidelines seek to incorporate and clarify internationally agreed methodology following the World Health Organization Laboratory Manual for the Examination and Processing of Human Semen 6th edition and publication of ISO 23162:2021.
View Article and Find Full Text PDFIntroduction: Progress in male contraception development faces the challenge of a lack of regulatory precedent and guidelines on the evidence (trial design and primary endpoint) required for marketing approval. Moreover, the development of a male contraceptive is complicated by the fact that the clinical treatment effect; prevention of pregnancy, is not measured in the patient receiving the intervention.
Discussion: Regulatory precedent and guidelines exist for female hormonal contraceptives but their applicability to male contraceptive products likely varies based on the mode of action and the anticipated pharmacodynamic effects of the product.
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