The authors carried out clinical follow-up and psychological examinations of 40 patients suffering from leprosy and treated at the Astrakhan Institute for Leprosy Research. Under study there were acute psychogenic reactions arising in the patients on diagnosing the disease and putting them to the leprosery. Clinical variants of adequate situational reactions (21 patients) and anomalous neurotic and psychopathic ones (19 patients) are described. These reactions were found to depend on the premorbid characteristics of the patient's personality and influence the subsequent course of the underlying disease.
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Neurol Int
January 2025
Department of Brain Repair & Rehabilitation, Institute of Neurology, University College London, London WC1E 6BT, UK.
The differential diagnosis of acute-onset amnesia includes transient global amnesia (TGA), transient epileptic amnesia (TEA), and functional (or psychogenic) amnesia. The most common of these, TGA, is a rare but well-described condition characterised by a self-limited episode of dense anterograde amnesia with variable retrograde amnesia. Although the clinical phenomenology of TGA is well described, its pathogenesis is not currently understood, thus preventing the development of evidence-based therapeutic recommendations.
View Article and Find Full Text PDFMed Klin Intensivmed Notfmed
December 2024
Neurologische Klinik, Standort Gießen, Universitätsklinikum Gießen und Marburg, Klinikstraße 33, 35392, Gießen, Deutschland.
Epileptic seizures, which are often accompanied by a reduction in vigilance, are a common emergency. Every first-time epileptic seizure should be investigated further. Particular attention should be paid to whether it is an acute symptomatic seizure, which is an acute event characterized by a metabolic disorder or acute cerebral damage within a certain period of time, or possibly epilepsy.
View Article and Find Full Text PDFMol Metab
January 2025
Florida State University, Department of Psychology and Program in Neuroscience, Tallahassee, FL, USA.
Stress-induced behaviours are driven by complex neural circuits and some neuronal populations concurrently modulate diverse behavioural and physiological responses to stress. Glucagon-like peptide-1 (GLP-1)-producing preproglucagon (PPG) neurons within the lower brainstem caudal nucleus of the solitary tract (cNTS) are particularly sensitive to stressful stimuli and are implicated in multiple physiological and behavioural responses to interoceptive and psychogenic threats. However, the afferent inputs driving stress-induced activation of PPG neurons are largely unknown, and the role of PPG neurons in anxiety-like behaviour is controversial.
View Article and Find Full Text PDFExp Ther Med
December 2024
Clinic of Social and Family Medicine, School of Medicine, University of Crete, 71003 Heraklion, Greece.
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