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Quant Imaging Med Surg
December 2024
Department of Ultrasonic Medicine, West China Second Hospital of Sichuan University, Chengdu, China.
Background: Small fetuses include constitutional small for gestational age (SGA) and fetal growth-restricted (FGR) fetuses. Various adverse intrauterine environments can lead to FGR which has higher risk of abnormal perinatal outcome. The fetal heart is very sensitive to the effects of a negative intrauterine environment.
View Article and Find Full Text PDFJ Clin Lab Anal
December 2024
Medical Genetic Diagnosis and Therapy Center, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Clinical Research Center for Maternal-Fetal Medicine, National Key Obstetric Clinical Specialty Construction Institution of China, Fuzhou, China.
Background: The short arm of chromosome 16 is highly susceptible to homologous recombination through nonallelic genes. This results in microdeletions/microduplications that can lead to neurodevelopmental disorders. However, incomplete penetrance and phenotypic diversity after birth exacerbate the uncertainty in prenatal genetic counseling.
View Article and Find Full Text PDFBiochem Biophys Res Commun
December 2024
Department of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address:
Objective: To compare the sensitivity of photoacoustic imaging (PAI) in the detection of Intrauterine adhesions (IUA) at different grades with that of high frequency ultrasound (US), and to investigate whether PAI can evaluate IUA noninvasively and quantitatively by monitoring endometrial oxygenation.
Materials And Methods: In vivo high-frequency US/PAI dual-modality imaging was performed in12 rats with IUA and 5 control rats, the monolayer endometrial thickness on US (US-EMT) and the average oxygenation saturation of endometrium on PAI (PA-sO2 Avr) were measured respectively. HE, Masson and immunofluorescence staining were further conducted to investigate the monolayer endometrial thickness (HE-EMT), the number of endometrial glands (HE-EMG), the area ratio of endometrial fibrosis (FAr) and the mean fluorescence intensity of Vascular endothelial growth factor (VEGF) in endometrium (VEGF-MFI).
J Ultrasound Med
November 2024
Department of Obstetrics and Gynaecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
J Perinat Med
November 2024
Gynecologic, Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China.
Objectives: To evaluate the diagnostic value of ultrasound spectra of the middle cerebral artery (MCA) and umbilical artery (UA) blood flow in predicting adverse pregnancy outcomes.
Methods: Data from 202 late singleton pregnancies (32-34 weeks gestation) were analyzed. Group A included 155 normal pregnancies, while Group B comprised 47 high-risk pregnancies.
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