AI Article Synopsis
- Cats infected with Brugia pahangi showed antibodies to soluble antigens from various stages of the parasite (microfilariae, adults, and L3 larvae).
- Infected cats with a significant presence of microfilariae tested positive for antibodies to all three stages of the parasite.
- Cats that lost their microfilariae presence still had antibodies to the L3 and microfilarial antigens but not to the adult worm antigen, while those inoculated with irradiated L3 larvae reacted only to the L3 antigen.
Article Abstract
In cats infected with normal, or irradiated, infective (L3) larvae of Brugia pahangi counterimmunoelectrophoresis revealed the presence of antibody to soluble antigens derived from microfilariae, adults and infective larvae of the same parasite. Infected cats with a persistently high to moderate microfilaraemia gave positive precipitin reactions to L3, microfilarial and adult worm antigens. Cats which had become amicrofilaraemic had antibody to L3 and microfilarial antigens but not to adult worm antigen. Serum from cats inoculated with irradiated L3 larvae produced a precipitin reaction only to the L3 antigen.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1017/s0022149x00005241 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A new class of natural anthelmintics targeting lipid metabolism.
Nat Commun
January 2025
Center for Genomics and Systems Biology, New York University Abu Dhabi, Saadiyat Island, Abu Dhabi, United Arab Emirates.
Parasitic helminths are a major global health threat, infecting nearly one-fifth of the human population and causing significant losses in livestock and crops. Resistance to the few anthelmintic drugs is increasing. Here, we report a set of avocado fatty alcohols/acetates (AFAs) that exhibit nematocidal activity against four veterinary parasitic nematode species: Brugia pahangi, Teladorsagia circumcincta and Heligmosomoides polygyrus, as well as a multidrug resistant strain (UGA) of Haemonchus contortus.
View Article and Find Full Text PDFIntegrated Histological and Molecular Analysis of Filarial Species and Associated Wolbachia Endosymbionts in Human Filariasis Cases Presenting Atypically in Thailand.
Am J Trop Med Hyg
October 2024
Siriraj Integrative Center for Neglected Parasitic Diseases, Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Atypical presentations of filariasis have posed diagnostic challenges due to the complexity of identifying the causative species and the difficulties in both diagnosis and treatment. In this study, we present the integrative histological and molecular analysis of seven atypical filariasis cases observed in regions of nonendemicity of Thailand. All filariasis cases were initially diagnosed based on histological findings.
View Article and Find Full Text PDFAn Overview of Management Considerations for Mongolian Gerbils (), Cats (), and Dogs () as Hosts for Infection.
Comp Med
June 2024
Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, Georgia; Office of Animal Care and Use, Office of Research, University of Georgia, Athens, Georgia.
Lymphatic filariasis is a mosquito-borne parasitic infection affecting an estimated 51.4 million people. and are used in research because common nonprimate research species such as Mongolian gerbils (), cats (), and dogs () can maintain the life cycle of these species of filarial nematodes.
View Article and Find Full Text PDFOcular Brugia pahangi Filariasis Complicated by Severe Macular Damage in Thailand: Case Report and Literature Review.
Am J Trop Med Hyg
June 2024
Center of Excellence in Vector Biology and Vector-Borne Disease, Chulalongkorn University, Bangkok, Thailand.
Extralymphatic filariasis caused by filaria of zoonotic origins has been frequently reported in Thailand over recent years. Here, we report the first case of ocular filariasis in a 7.5-year-old Thai boy who initially presented with progressive conjunctival redness and blurred vision in his right eye.
View Article and Find Full Text PDFUnveiling zoonotic threats: molecular identification of sp. infection in a lion.
Front Vet Sci
April 2024
Parasitology Unit, Department of Veterinary Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
Article Synopsis
- - The study investigates the presence of a specific nematode infection in a lion from a zoo in Thailand, focusing on its potential as a zoonotic pathogen reservoir, primarily affecting pets like dogs and cats.
- - Blood samples from the lion were analyzed using staining methods and PCR techniques to identify the nematode at the genus and species level, which revealed a high genetic similarity to known nematode parasites.
- - This research marks the first molecular identification of the infection in a lion, suggesting that these animals could pose a public health risk, and highlights the importance of using molecular techniques for better diagnosis and control of such zoonotic infections.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!