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Cervicovaginal microbiome and natural history of Chlamydia trachomatis in adolescents and young women.
Cell
January 2025
Departments of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, NY, USA; Department of Pediatrics (Genetic Medicine), Albert Einstein College of Medicine, Bronx, New York, NY, USA; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, NY, USA; Department Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, New York, NY, USA. Electronic address:
This study investigated the cervicovaginal microbiome's (CVM's) impact on Chlamydia trachomatis (CT) infection among Black and Hispanic adolescent and young adult women. A total of 187 women with incident CT were matched to 373 controls, and the CVM was characterized before, during, and after CT infection. The findings highlight that a specific subtype of bacterial vaginosis (BV), identified from 16S rRNA gene reads using the molBV algorithm and community state type (CST) clustering, is a significant risk factor for CT acquisition.
View Article and Find Full Text PDFDiversifying the Surgical Workforce: Understanding Barriers to Inform Solutions.
J Surg Educ
January 2025
Division of Vascular and Endovascular Surgery, University of Massachusetts Chan Medical School, Worcester, Massachusetts.
Objectives: Race and gender concordance between physicians and patients is associated with reductions in healthcare disparities. However, the diversity of the medical workforce does not mirror the population; some of the greatest deficiencies exist in the surgical workforce. We conducted a pilot study focused on early recruitment of diverse college students in our region, with a concurrent needs assessment of their specific barriers to entering the field of surgery.
View Article and Find Full Text PDFPredictors of Service Awareness: Results from a Community Survey in an Urban Area.
J Gerontol Soc Work
January 2025
Wayne State University School of Social Work, Detroit, USA.
We examined information seeking strategies and predictors of service awareness from a 2019 survey of Detroit area adults. Participants were age 60+ (mean age = 72.10; SD = 8.
View Article and Find Full Text PDFVaricella challenges: A case of respiratory tract complications in an elderly patient.
Narra J
December 2024
Department of Dermatology Venereology and Aesthetic, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Varicella, caused by the varicella-zoster virus (VZV), is rarely reported in the elderly but often complicates with pneumonia. In this case report, we present a case of varicella pneumonia in the elderly. A 60-year-old man presented to the emergency room with vesicles filled with clear fluid that had appeared all over the body for the past four days.
View Article and Find Full Text PDFGenetic Variants Associated with the Biochemical Response to Vitamin D3 in the Multi-Ethnic Study of Atherosclerosis.
J Clin Endocrinol Metab
January 2025
Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA.
Context: The response to treatment with vitamin D varies between patients.
Objective: To identify genetic variants associated with the biochemical response to vitamin D3 supplementation.
Design: Randomized placebo-controlled trial conducted between 2017 and 2019.
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