AI Article Synopsis
- The study aimed to analyze changes in irradiated mandibular bone by examining how bone tissue lesions develop and affect the area.
- Researchers assessed the vitality of jaw fragments by counting inhabited and empty lacunae, using methylene blue for staining, and compared these results with microradiographic images.
- A surprising finding was that areas with the most damage had the highest percentages of osteocytes, raising questions about how to minimize complications from radiotherapy and its repair attempts.
Article Abstract
To understand the changes of the irradiated mandibular bone, we tried to define, in space, how the lesions of the osseous tissue appear and involve. We estimated the vitality of the removed jaw fragments by counting the number of inhabited lacunae (I.L.) and empty lacunae (E.L.) in the sections, without previous decalcification, after surface staining with methylene blue. The results, expressed as percentages of the total amount of osteocytes lacunae, have been compared with the microradiographic aspect of the sections. The most paradoxical finding is that the highest percentages of osteocytes appear in the most destroyed areas. As a conclusion, one may wonder how to proceed to avoid the radiotherapy being followed by attempts for repair: attempts which, indeed, are the source of the complications.
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