AI Article Synopsis
- Somatostatin-28(1-12) levels were found to be higher in the hypophysial portal blood compared to peripheral blood in rats.
- Electrical stimulation of the median eminence significantly increased the release of somatostatin-28(1-12) into the portal blood by 4 to 5 times.
- These findings suggest that somatostatin-28(1-12) may function as a neurohormone or neurotransmitter in physiological processes.
Article Abstract
Somatostatin-28(1-12)-like immunoreactivity was measured in extracts of rat hypophysial portal blood and peripheral blood. The concentration of somatostatin-28(1-12) was higher in portal than in peripheral extracts, and its release into portal vessel blood was increased 4- to 5-fold by electrical stimulation of the median eminence. These results show that somatostatin-28(1-12) may be a physiological neurohormone and/or neurotransmitter.
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| http://dx.doi.org/10.1159/000123871 | DOI Listing |
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