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Stopping of adalimumab in juvenile idiopathic arthritis-associated uveitis (ADJUST): a multicentre, double-masked, randomised controlled trial.
Lancet
January 2025
Francis I Proctor Foundation, University of California San Francisco, San Francisco, CA, USA; Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA; Institute for Global Health Sciences, University of California San Francisco, San Francisco, CA, USA.
Background: Adalimumab is an effective treatment for juvenile idiopathic arthritis-associated uveitis. Data are scarce on the effects of discontinuing adalimumab after control of the disease had been reached. We aimed to assess efficacy and safety of discontinuing treatment in patients with juvenile idiopathic arthritis-associated uveitis.
View Article and Find Full Text PDFMolecular investigation of tick-borne pathogens from different regions of Morocco.
Ticks Tick Borne Dis
November 2024
National Institute of Health Doutor Ricardo Jorge, Center for Vectors and Infectious Diseases, Portugal; Institute of Environmental Health (ISAMB), Lisbon, Portugal.
Tick-borne pathogens are a worldwide threat to public health that can only be mitigated by knowledge on tick-host associations coupled with surveillance of their infection by pathogenic microorganisms. This information is not equally available throughout tick vector distribution range and is deficient in some geographical areas. In this study we did a molecular survey of tick-borne pathogens associated with different tick species in Morocco.
View Article and Find Full Text PDFA Clinic-Level Approach to Improve Uptake of First COVID-19 Vaccine Dose in Primary Care.
J Health Care Poor Underserved
November 2024
This quality improvement initiative aimed to increase first dose of COVID-19 vaccinations during pediatric/adolescent clinic visits. Four plan-do-study-act cycles were performed with creation of eligibility lists and increasing health educator (HE) engagement. Statistical process control analysis assessed vaccine receipt over time.
View Article and Find Full Text PDFComparison of baseline painted turtle (Chrysemys picta) health assessments at a confined disposal facility and a protected coastal marsh in southwestern Lake Erie, Ohio, USA.
J Wildl Dis
November 2024
One Welfare & Sustainability Center, The Ohio State University College of Veterinary Medicine Department of Veterinary Preventive Medicine, Sisson Hall, 1920 Coffey Road, Columbus, Ohio 43210, USA.
Article Synopsis
- * Turtles from the CDF showed signs of higher stress, including elevated glucose levels and altered blood metrics, compared to those from the PCM, which appeared healthier.
- * Additionally, some turtles tested positive for Chlamydia, with a small number also showing co-infection with herpesvirus, highlighting the need to monitor the impacts of human-altered habitats on wildlife health.
Vaccines for preventing Ebola virus disease.
Cochrane Database Syst Rev
November 2024
Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Article Synopsis
- The protocol outlines a Cochrane Review aimed at evaluating the effectiveness of vaccines for preventing Ebola virus disease.
- The primary focus is on individuals who have been directly exposed or may have been exposed to the Ebola virus.
- The review will analyze existing studies to determine how well these vaccines perform in preventing the disease in those at risk.
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