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In Vitro Anthelmintic Effect of Mexican Plant Extracts and Partitions Against and .
Plants (Basel)
December 2024
Grupo de Enfermedades Infecciosas y Tropicales (e-INTRO), Instituto de Investigación Biomédica de Salamanca-Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca (IBSAL-CIETUS), Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain.
Parasitic diseases represent a significant global public health concern. Two clinically important parasites of high prevalence rates are and . However, the limitations of currently used nematocidal drugs highlight the urgent need for novel treatment approaches.
View Article and Find Full Text PDFSurvival of and in Experimentally Infected Wild Boar Muscle Tissue under Freezing and Environmental Conditions.
Iran J Parasitol
January 2024
Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Sciences, University of Buenos Aires, Buenos Aires, Argentina.
Background: The aim of this study was to investigate the survival of and in decaying wild boar tissue and assess their freezing tolerance in experimentally infected animals.
Methods: The present study was conducted in Buenos Aires City, Argentina during the 2018-2019 period. Two wild boars were used, one infected with 20,000 muscle larvae (ML) of and the other with .
Molecular and biological characterization of transforming growth factor-β homolog derived from Trichinella spiralis.
Sci Rep
December 2024
Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
The cytokine homologs, particularly transforming growth factor (TGF)-β, is a crucial immunomodulatory molecule and involved in growth and developmental processes in several helminths. In this study, the basic properties and functions of T. spiralis TGF-β homolog 2 (TsTGH2) were characterized using bioinformatics and molecular biology approaches.
View Article and Find Full Text PDFInterleukin-13 partly induced by the NLRP3 inflammasome promotes Trichinella spiralis encapsulation in infected mice.
Vet Parasitol
December 2024
College of Veterinary Medicine, Jilin Agricultural University, Changchun 130118, China; Jilin Provincial Engineering Research Center of Animal Probiotics, Jilin Provincial Key Laboratory of Animal Microecology and Healthy Breeding, Jilin Agricultural University, Changchun 130118, China; Engineering Research Center of Microecological Vaccines (Drugs) for Major Animal Diseases, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. Electronic address:
Trichinella spiralis infection is a serious parasitic zoonosis in which a collagenous capsule surrounding the larva is developed in the striated muscle cells. However, the mechanism of T. spiralis encapsulation is currently poorly understood.
View Article and Find Full Text PDFTrichinella spiralis excretory/secretory antigens ameliorate porcine epidemic diarrhea virus-induced mucosal damage in porcine intestinal oganoids by alleviating inflammation and promoting tight junction.
Int J Parasitol
December 2024
State Key Laboratory for Animal Disease Control and Prevention, Key Laboratory of Veterinary Parasitology of Gansu Province, Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Disease, Yangzhou 225009, China. Electronic address:
Trichinella spiralis and porcine epidemic diarrhea virus (PEDV) are two infectious swine pathogens. Parasite excretory/secretory antigens play critical roles in various disease processes. To explore the coexistence mechanism of two pathogens infecting the same host, the intestinal organoid was utilized to reproduce these biological processes.
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