At the Schieffelin Leprosy Research and Training Centre, Karigiri, India, data were assembled on all 58 living patients with lepromatous leprosy residing in Gudiyatham Taluk who had been registered in 1960 or earlier. They had received domiciliary oral DDS monotherapy for greater than 20 years. Fifty-one of the 58 patients were currently smear negative and clinically inactive. Patients with a Bacterial Index that had at some time been greater than or equal to 2+ were currently found smear positive more frequently than the remaining patients.
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