AI Article Synopsis

  • The study observed 58 patients with isolated or associated subaortic stenosis from 1961 to 1980, ages 2 to 42, focusing on clinical signs, left ventricle overload, and gradient levels.
  • Preoperative evaluations showed poor correlations among clinical, electrocardiographic, and hemodynamic parameters, with 41 patients undergoing surgery—two of whom died shortly after.
  • Post-surgery, patients showed significant improvement in symptoms and a notable decrease in systolic gradient, supporting early surgical intervention as the condition evolves differently than typical congenital aortic stenosis.

Article Abstract

Fifty eight patients with isolated with discrete subaortic stenosis or in association with just another heart defect, were studied between 1961 and 1980. The age range was between 2 and 42 years. The evaluation of each case was done according to clinical manifestations, systolic overloading of the left ventricle and the amount of the systolic gradient. There is a poor correlation between the clinical, electrocardiographic and hemodynamic parameters according to the student t test in the preoperative evaluation. Forty-one patients were operated, two of them died in the early post-operative period. There was a good clinical evolution with significant values comparing pre and post-operative symptoms. The decrease in the systolic gradient in 26 cases after surgery was significative (p less than or equal to 0.005). Based on the natural history of this malformation and on the results obtained with the surgical treatment, we may conclude that there is surgical indication once the diagnosis is made, because this malformation has a completely different evolution compared with other forms of congenital aortic stenosis.

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