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Rastermap: a discovery method for neural population recordings.
Nat Neurosci
January 2025
Howard Hughes Medical Institute Janelia Research Campus, Ashburn, VA, USA.
Article Synopsis
- The text discusses the challenges in analyzing large-scale neural data and highlights the importance of visualization methods to identify activity patterns in neurons.* -
- It introduces 'Rastermap', a new visualization technique that organizes neurons based on their activity patterns and allows researchers to explore recordings from various animal models, including mice and zebrafish.* -
- The effectiveness of Rastermap is benchmarked through simulations, and the text also notes that there are specific high-dimensional scenarios where this method and similar algorithms may fail to provide clear insights.*
Atomic-engineered gradient tunable solid-state metamaterials.
Proc Natl Acad Sci U S A
September 2024
Department of Electrical and Computer Engineering, National University of Singapore, Singapore 117583, Singapore.
Metamaterial has been captivated a popular notion, offering photonic functionalities beyond the capabilities of natural materials. Its desirable functionality primarily relies on well-controlled conditions such as structural resonance, dispersion, geometry, filling fraction, external actuation, etc. However, its fundamental building blocks-meta-atoms-still rely on naturally occurring substances.
View Article and Find Full Text PDFAssessing Human Influence and Vegetative Dune Dynamics on Barrier Islands via Satellite Raster Classification.
Environ Manage
September 2024
GMC Network, Birmingham, AL, USA.
Barrier islands support ecological diversity and offshore ecosystems and provide critical protection to coastal communities. Climate change has intensified the frequency and severity of hurricanes affecting these islands, leading to ongoing erosion. The primary goal of this study was to explore the relationship between human intervention such as development and construction and the vegetative dune systems on Gulf Coast barrier islands in Alabama and Mississippi, USA.
View Article and Find Full Text PDFAdvanced analysis of single-molecule spectroscopic data.
Biophys Rep (N Y)
September 2024
Department of Physics, University of Pretoria, Pretoria, Gauteng, South Africa; Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Pretoria, Gauteng, South Africa; National Institute of Theoretical and Computational Sciences (NITheCS), South Africa. Electronic address:
We present Full SMS, a multipurpose graphical user interface (GUI)-based software package for analyzing single-molecule spectroscopy (SMS) data. SMS typically delivers multiparameter data-such as fluorescence brightness, lifetime, and spectra-of molecular- or nanometer-scale particles such as single dye molecules, quantum dots, or fluorescently labeled biological macromolecules. Full SMS allows an unbiased statistical analysis of fluorescence brightness through level resolution and clustering, analysis of fluorescence lifetimes through decay fitting, as well as the calculation of second-order correlation functions and the display of fluorescence spectra and raster-scan images.
View Article and Find Full Text PDFA Fast and Interactive Augmented Reality System for PET/CT-guided Intervention of Neuroblastoma.
Proc SPIE Int Soc Opt Eng
February 2024
Center for Imaging and Surgical Innovation, University of Texas at Dallas, TX.
Neuroblastoma is the most common type of extracranial solid tumor in children and can often result in death if not treated. High-intensity focused ultrasound (HIFU) is a non-invasive technique for treating tissue that is deep within the body. It avoids the use of ionizing radiation, avoiding long-term side-effects of these treatments.
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