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Pharmacological and Herbal Approach to Diabetes Mellitus Type 2 Management: A Comparative Analysis of Conventional Therapy and Alternative Remedy.
Ann Pharm Fr
March 2025
Department of Pathology, Cholistan University of Veterinary and Animal Science, Bahawalpur, 63100, Pakistan. Electronic address:
Diabetes mellitus is a heterogeneous metabolic disorder that affects the metabolism of protein, fats, and carbohydrates due to the destruction of beta-cells resulting disruptions in insulin action/insulin secretion. According to International Diabetes Federation (IDF) prevalence of 90% people with diabetes has type 2 diabetes is driven by socio-economic, demographic, environmental, and genetic factors. DM type 2 sparks myriad of debilitating disease needs management to cure it.
View Article and Find Full Text PDFManagement of Angina Pectoris.
Trends Cardiovasc Med
March 2025
Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy; Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. Electronic address:
Angina pectoris, a primary manifestation of ischemic heart disease, imposes a significant clinical and economic burden globally. This review highlights recent advancements in the management of angina, emphasizing a patient-centred approach that integrates pharmacological, interventional, and lifestyle strategies to reduce cardiovascular risk and improve patient outcomes. For obstructive coronary artery disease, optimal medical therapy represents the cornerstone of treatment.
View Article and Find Full Text PDFAntioxidant Supplementation for Management of Gestational Diabetes Mellitus in Pregnancy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Curr Nutr Rep
March 2025
Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, 3220, Australia.
Purpose Of Review: Gestational diabetes mellitus (GDM) is the most common medical complication of pregnancy globally. Hyperglycaemia and associated production of reactive oxygen species can lead to oxidative stress in pregnancy. However, the potential effectiveness of increased antioxidant intake in the management of GDM has not been widely examined.
View Article and Find Full Text PDFVDAC1 Inhibition Mitigates Inflammatory Status and Oxidative Stress in Epileptic Mice Treated with the Ketogenic Diet.
Neurochem Res
March 2025
Department of Neurosurgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Due to the pleiotropic effects of ketogenic diet (KD) on pathophysiology, including inflammation and oxidative stress, medical personnels have been intensively exploring the application of it in the management of epilepsy. Meanwhile, the voltage-dependent anion channel 1 (VDAC1) is believed to be involved in regulating inflammatory and oxidative stress processes. However, the correlation between KD and VDAC1 in epilepsy has not been elucidated.
View Article and Find Full Text PDFBackground and objective Lifestyle modification (related to diet and physical activity) is a key part of treatment for patients diagnosed with type 2 diabetes or hypertension. However, many patients are unable to follow the prescribed lifestyle modifications. This study aimed to investigate the causes of non-adherence in Indian adult patients with newly diagnosed type 2 diabetes mellitus (T2DM) or hypertension, who were advised lifestyle modifications along with pharmacotherapy.
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