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Native joint septic arthritis (SA) is a severe, potentially life-threatening condition characterized by the invasion of synovial fluid and membrane by pathogens, most commonly bacteria. The rising frequency of intra-articular procedures such as joint aspirations and injections has led to increased concern regarding iatrogenic septic arthritis. This mini-review aims to summarize current understanding of the incidence, risk factors, bacterial etiology, and strategies for preventing SA associated with intra-articular procedures.

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No detrimental effect on the hand microbiome of health care staff by frequent alcohol-based antisepsis.

Am J Infect Control

November 2024

Section Antiseptic Stewardship of the German Society of Hospital Hygiene e. V., Berlin, Germany; Friedrich Loeffler-Institute of Medical Microbiology-Virology, University Medicine Greifswald, Greifswald, Germany. Electronic address:

Background: The importance of ethanol-based hand rubs (EBHRs) to prevent health care-associated infections is undisputed. However, there is a lack of meaningful data regarding the influence of EBHRs on skin microbiome.

Methods: Four nurses in a neonatal intensive care unit were included.

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S2k-Guideline hand antisepsis and hand hygiene.

GMS Hyg Infect Control

September 2024

German X-ray Society and German Society for Interventional Radiology and Minimally Invasive Therapy, Berlin. Germany.

The consensus-based guideline "hand antisepsis and hand hygiene" for Germany has the following sections: Prevention of nosocomial infections by hygienic hand antisepsis, prevention of surgical site infections by surgical hand antisepsis, infection prevention in the community by hand antisepsis in epidemic or pandemic situations, hand washing, selection of alcohol-based hand rubs and wash lotions, medical gloves and protective gloves, preconditions for hand hygiene, skin protection and skin care, quality assurance of the implementation of hand hygiene measures and legal aspects. The guideline was developed by the German Society for Hospital Hygiene in cooperation with 22 professional societies, 2 professional organizations, the German Care Council, the Federal Working Group for Self-Help of People with Disabilities and Chronic Illness and their Family Members, the General Accident Insurance Institution Austria and the German-speaking Interest Group of Infection Prevention Experts and Hospital Hygiene Consultants.

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Background: Hand hygiene is one of the most important hygiene measures to prevent healthcare-associated infections. Well-functioning hand rub dispensers are the foundation of hand hygiene but are often overlooked in research. As the point of origin for hand hygiene, dispensers not only promote compliance through ease of use, but also strongly influence the amount of hand rub used per disinfection.

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Modern medicine is well-versed in aseptic and infection control practices, such as hand hygiene, proper use of disinfectants, and personal protective equipment. The early 1800s lacked any concept of effective antisepsis because they predominantly believed in the miasma theory (now abandoned), which believed that disease was caused by bad air coming out of rotting organic matter. In the era of "miasma theory," Ignaz Semmelweis dared to pave the way for germ theory disease.

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