Case reports of 4 patients with Rotor syndrome are given, including clinical chemistry values for liver function, BSP-test, histology, as well as sequential scintigraphy results with 131I-BSP. All results were normal, except serum bilirubin, which was increased, conjugated bilirubin making up for the largest part of the increase. The BSP-curve showed elevated 45-minute-values and liver scintigraphy disturbed hepatic uptake and storage of BSP. Therapy with phenobarbital led to a decrease of serum levels of bilirubin and BSP-retention.
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