Eyelid motor impersistence is the impossibility shown by some people to maintain voluntary lid closure for a long period. This disorder is not exceptional, and the authors have seen fifteen cases over a short period of time. The phenomenon represents a form of apraxia, and occurs only when the minor hemisphere is damaged with a lesion of the parietal lobe. Diagnosis can often be confirmed by a CAT scan: of the three observations reported by the authors, two were tumors and one a thalamic hematoma. For some authors, motor impersistence is a manifestation of neglect and they include it within the general problem of interhemispheric balance.
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NeuroRehabilitation
April 2024
Department of Rehabilitation Science, Faculty of Health Sciences, Nara Gakuen University, Nara, Japan.
Background: Patients with cerebrovascular disorders (CVDs) tend to exhibit impulsive behaviour without controlling their movements, leading to difficulty in performing activities of daily living and an increased risk of accidents. This hastiness, termed 'pacing impairment', has been studied but is not fully understood.
Objective: To experimentally examine the kinetic features of pacing impairment by focusing on changes in speed and investigating neuropsychological substrates.
Front Neurol
June 2023
Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan.
Background: Chorea is a movement disorder characterized by abrupt, rapid, and uncontrollable, random movements from one part of the body to another with motor impersistence. Sporadic chorea is rarely caused by either thyrotoxicosis or Moyamoya disease (MMD).
Methods And Results: In this case report, we describe a female patient with chorea with the rare coexistence of Graves' disease and Moyamoya disease.
Mov Disord Clin Pract
May 2022
Division of Neurology, Department of Medicine University of Toronto Toronto Ontario Canada.
Background: Progressive supranuclear palsy (PSP)-pallido-nigro-luysian atrophy (PNLA) is a neuropathological entity thought to be a variant of classic PSP. Clinical features and pathologic hallmarks are the same in both conditions; however, age and order of symptom onset, disease duration and prognosis, and distribution and density of pathology differentiate the 2 entities.
Objectives: This study presents a PSP-PNLA case confirmed pathologically with a clinical presentation of hemichorea/ballism, spasticity, progressive hemiparesis, and a frontal behavioral syndrome with relative cognitive sparing early in the disease course.
Tremor Other Hyperkinet Mov (N Y)
January 2022
Yale School of Medicine, Department of Neurology, US.
Am J Physiol Cell Physiol
July 2020
Department of Biological Sciences, Wright State University, Dayton, Ohio.
Huntington's disease (HD) patients suffer from progressive and debilitating motor dysfunction for which only palliative treatment is currently available. Previously, we discovered reduced skeletal muscle Cl channel (ClC-1) and inwardly rectifying K channel (Kir) currents in R6/2 HD transgenic mice. To further investigate the role of ClC-1 and Kir currents in HD skeletal muscle pathology, we measured the effect of reduced ClC-1 and Kir currents on action potential (AP) repetitive firing in R6/2 mice using a two-electrode current clamp.
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