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Dupilumab induced ocular surface diseases: an analysis of FAERS database, literature review and disease-gene interaction networks.
Expert Opin Drug Saf
January 2025
Department of Pharmacy, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong, China.
Background: Adverse events (AE) in dupilumab induced ocular surface diseases (DIOSD) have raised concerns regarding its safety. The objective of this study was to evaluate DIOSD by employing database analysis and clinical case review, along with mechanism analysis.
Research Design And Methods: Database AE data were extracted from FAERS from 2017 Quarter 1 (Q1) to 2023 Q1.
Maternal immunization impairs lymphoma growth and CNS/ocular metastasis in the offspring.
Front Immunol
January 2025
Alexander Silberman Institute of Life Science, The Hebrew University of Jerusalem, Jerusalem, Israel.
Maternal immunization is an important tool directed against a variety of infectious maladies in the offspring. A complementary, but less explored area is the use of maternal immunization in the prevention and treatment of childhood cancers. This in part stems from the lack of adequate experimental model systems.
View Article and Find Full Text PDFComparison of Intraocular Lens Formulas in Patients With Postoperative Refractive Surprise.
Cureus
December 2024
Ophthalmology, University of Washington, Seattle, USA.
Objective: This study investigates the refractive accuracy of eight intraocular lens (IOL) power calculation formulas in patients with postoperative refractive surprise after phacoemulsification. It aims to determine if a different formula could result in better refractive outcomes in these eyes.
Methods And Analysis: We retrospectively reviewed consecutive patients undergoing uncomplicated phacoemulsification as a sole procedure between March 2007 and September 2020 at the University of Washington by glaucoma subspecialists as part of a study investigating cataract surgery in normal eyes.
Effects of Lotrafilcon A and Senofilcon A Bandage Contact Lenses on Visual Outcome and Ocular Comfort After Photorefractive Keratectomy.
Turk J Ophthalmol
December 2024
Muğla Sıtkı Koçman University Faculty of Medicine, Department of Ophthalmology, Muğla, Türkiye.
Objectives: To compare the efficacy of two different silicone hydrogel bandage contact lenses (BCLs) in terms of visual rehabilitation and ocular discomfort following photorefractive keratectomy (PRK).
Materials And Methods: This prospective study included 60 eyes of 30 patients who underwent bilateral PRK surgery to correct myopia and/or astigmatism refractive errors. Following surgery, lotrafilcon A BCLs were applied to the right eye and senofilcon A BCLs were applied to the left eye.
[Preliminary clinical observation of ocular biological parameters in transfusion-dependent β-thalassemia children].
Zhonghua Yan Ke Za Zhi
January 2025
Department of Ophthalmology, Affiliated Hospital of Guangdong Medical University, Zhanjiang524000, China.
To observe the characteristics of ocular biological parameters in children with transfusion-dependent β-thalassemia (TDT) and the effect of iron chelator treatment on them. This was a cross-sectional study. Thirty-two children with TDT (TDT group) and 64 healthy children (control group) who were treated in the Affiliated Hospital of Guangdong Medical University from October 2022 to June 2023 were included.
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